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Saudi Journal of Kidney Diseases and Transplantation
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ORIGINAL ARTICLE Table of Contents   
Year : 1995  |  Volume : 6  |  Issue : 2  |  Page : 136-139
Prevalence of Hepatitis C Antibodies Among Hemodialysis Patients in the Western Province of Saudi Arabia

1 Jeddah Kidney Center, Jeddah, Saudi Arabia
2 Department of Nephrology, College of Medicine, King Saud University, Riyadh, Saudi Arabia
3 Department of Gastroenterology, College of Medicine, King Saud University, Riyadh, Saudi Arabia
4 King Abdulaziz Hospital, Jeddah, Saudi Arabia
5 Ministry of Health, Riyadh, Saudi Arabia
6 Al Noor Hospital, Makkah, Saudi Arabia
7 King Faisal Hospital, Taif, Saudi Arabia

Correspondence Address:
Faissal A.M Shaheen
Consultant Nephrologist and Director, Jeddah Kidney Center, King Fahd Hospital, Jeddah
Saudi Arabia
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PMID: 18583852

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We studied 408 patients on maintenance hemodialysis at four different centers in the Western province of Saudi Arabia to assess the prevalence of antibody against Hepatitis C Virus (HCV) and the possible risk factors. There were 212 males and 196 females with a mean age of 42.9 13.9 years (range 12 to 75 years). They were on dialysis for a period between 3 to 140 months with a mean of 52.2 + 38 months. Assay for anti-HCV was made by second generation ELISA. A total of 295 patients (72.3%) tested positive. The prevalence rates varied considerably among the four centers studied and were as follows: the center at Jeddah, 62.7%; two centers at Makkah, 87% and 79.7% respectively and one center at Taif, 80.9%. A total of 311 patients had received varying number of blood transfusions. Of these, 230 (74%) were anti-HCV positive as against 97 patients who were never transfused of whom 65 (67%) were positive. This difference did not reach statistical significance (P = 0.22). Similarly, we found no significant correlation between the anti-HCV prevalence rates and serum alanine transaminase levels (P = 0.93). Our study further confirms that there are routes other than blood transfusion involved in the transmission of the HCV and there is a need to determine these routes in order to prevent the spread of this virus.

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