Home About us Current issue Back issues Submission Instructions Advertise Contact Login   

Search Article 
Advanced search 
Saudi Journal of Kidney Diseases and Transplantation
Users online: 1274 Home Bookmark this page Print this page Email this page Small font sizeDefault font size Increase font size 

CASE REPORT Table of Contents   
Year : 1995  |  Volume : 6  |  Issue : 2  |  Page : 206-210
Progression of Hepatitis C Infection in a Renal Transplant Recipient: A Case Report

Department of Nephrology, Riyadh Armed Forces Hospital, Riyadh, Saudi Arabia

Correspondence Address:
Abdalla H Abdalla
Department of Renal Medicine, Riyadh Armed Forces Hospital P.O. Box 7897, Riyadh 11159
Saudi Arabia
Login to access the Email id

PMID: 18583865

Rights and Permissions

We present a patient with hepatitis C virus (HCV) infection who developed chronic active hepatitis (CAH) after renal transplantation. Alpha-interferon (a-IF) therapy was administered in view of deteriorating liver biochemistry. Liver histology at this stage showed features suggestive of chronic active hepatitis (CAH). The patient had stable graft function. Therapy with a-IF resulted in noticeable biochemical response within two weeks of commencement. An episode of steroid resistant renal allograft rejection occurred after 10 weeks of a-IF therapy which responded well to anti-lymphocyte globulin. Since then, the CAH has gradually progressed on to the development of cirrhotic changes and hepato-cellular carcinoma after 10 years following transplantation. Our case indicates that liver disease in anti­HCV positive patients can follow a serious course following renal transplantation.

Print this article  Email this article

  Similar in PUBMED
    Search Pubmed for
    Search in Google Scholar for
  Related articles
   Citation Manager
  Access Statistics
   Reader Comments
   Email Alert *
   Add to My List *
 * Requires registration (Free)

 Article Access Statistics
    PDF Downloaded181    
    Comments [Add]    

Recommend this journal