Home About us Current issue Back issues Submission Instructions Advertise Contact Login   

Search Article 
  
Advanced search 
 
Saudi Journal of Kidney Diseases and Transplantation
Users online: 2525 Home Bookmark this page Print this page Email this page Small font sizeDefault font size Increase font size 
 

LETTER TO THE EDITOR Table of Contents   
Year : 1999  |  Volume : 10  |  Issue : 1  |  Page : 70
Ramdionuclide Assessment of Patients with Urinary Tract Infection and Vesico-ureteric Reflux Using Tc-99m-Dimercaptosuccinic Acid


Department of Diagnostic Radiology, King Hussein Medical Center, P.O. Box 13311, Amman 11942, Jordan

Click here for correspondence address and email
 

How to cite this article:
Al-Kaylani H. Ramdionuclide Assessment of Patients with Urinary Tract Infection and Vesico-ureteric Reflux Using Tc-99m-Dimercaptosuccinic Acid. Saudi J Kidney Dis Transpl 1999;10:70

How to cite this URL:
Al-Kaylani H. Ramdionuclide Assessment of Patients with Urinary Tract Infection and Vesico-ureteric Reflux Using Tc-99m-Dimercaptosuccinic Acid. Saudi J Kidney Dis Transpl [serial online] 1999 [cited 2019 Nov 18];10:70. Available from: http://www.sjkdt.org/text.asp?1999/10/1/70/37307
Author's Reply,

I would like to thank Dr. Abdurrahman, whose letter to the editor appeared in the past issue,, for reading the article as well as commenting on it and here I want to clarify certain points.

It is well known now that DMSA scanning bas become one of he most sensitive tests for detecting renal involving in patients with UTI especially in those with VUR. [1],[2] It is true that some investigators used DMSA scanning in the acute stage to detect early renal involvement and they followed up their patients with another DMSA scanning 2-6 months or a year after the acute infection. [3],[4],[5] They found that some defects were reversible in the follow up scanning as mentioned by Dr. Abdurrahman.

The aim of our study w sot identify affected kidney in patients with UTI ad VUR and, for the purpose of this study, we were not concerned with reversal of these lesions seen in the acute stage. So we only performed a single study 4-6 weeks after the subsiding of the acute infection (and if we add the period of treatment this well make a total time of 1.5-2 months). We think this period is enough for most (perhaps not all) of the reversible lesions to clear, and our results will give a satisfactory correlation with the degree of renal damage and allow a correlation with VUR to be made.

It is true that IVU is rarely used now in the initial evaluation of patients with UTI, but some investigators still think that it ahs some role [6] in the management of these patients. In our study we used IVU to blood for any structural abnormality (Besides reflux) that might contribute to patient's problem. Patients with positive results were excluded form one study (e.g. patients with PUJ obstruction).

 
   References Top

1.Jaya G, Bal CS, Padhy AK, et al. Radionuclide studies in the eval8ation of urinary tract infectios. Indialn Pediatr 1996;33(8):635-40.  Back to cited text no. 1    
2.Clarke SE, Smellie JM, Prescod M, Gurney S, West DJ. Technetium-99m-DMSA studies in pediatric urinay infection. JK Nucl Med 1996;37(5):823-8.  Back to cited text no. 2    
3.Jakobsson B, Soderlundh S, Berg U. diagnostic significance of 99m Tc­demercaptosuccinic acid (DMSA) scintigraphy in urinary tract infection. Arch Dis Dis Child 1992;67(11):1338-42.  Back to cited text no. 3    
4.Metesanz Perez JL, Fernandez M. The utility of gammography with Tc-99m-DMSA in the protocol for studying UTI. An esp Pediatr 1998;48(1):21-4.  Back to cited text no. 4    
5.Jakobsson B, Svensson L. transient pyelonephritic changes on 99m­Technitium-dimercaptosuccinic acid scan for at least five months after infection. Acta Pediatr 1997;86(8):803-7.  Back to cited text no. 5    
6.Hansen A, Wegner AA, Levard LD, Nielsen JT. Diagnostic imaging in children with urinary tract infection: the role of intravenous rography. Acta Paediatr 1995;84(1):84-9.  Back to cited text no. 6    

Top
Correspondence Address:
Hussan Al-Kaylani
Department of Diagnostic Radiology, King Hussein Medical Center, P.O. Box 13311, Amman 11942
Jordan
Login to access the Email id


PMID: 18212419

Rights and Permissions




 

Top
 
 
    Similar in PUBMED
    Search Pubmed for
    Search in Google Scholar for
    Email Alert *
    Add to My List *
* Registration required (free)  
 


 
    References
 

 Article Access Statistics
    Viewed1187    
    Printed39    
    Emailed0    
    PDF Downloaded223    
    Comments [Add]    

Recommend this journal