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Saudi Journal of Kidney Diseases and Transplantation
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ARTICLE Table of Contents   
Year : 1999  |  Volume : 10  |  Issue : 3  |  Page : 325-332
Treatment of Hypertension in Diabetes


Department of Medicine, University of Melbourne, Heidelberg, Australia

Correspondence Address:
Mark Emmanuel Cooper
Department of Medicine, Austin and Repatriation Medical Center, W. Heidelberg, Victoria 3081
Australia
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PMID: 18212442

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Patients with type I and II diabetes mellitus represent a population at high risk of the cardiovascular, cerebrovascular and renal effects of hypertension. Antihypertensive therapy should be considered for those with blood pressures above 130/85 mmHg with the aim to reduce levels below 125/75 especially for those with microalbummuria or diabetic nephropathy. Hypertension tends to occur on a background of multiple other risk factors. Life­style changes such as increased exercise and reduced salt intake, when combined with medication should improve the blood pressure response. On the currently available data, an Angiotensin Converting Enzyme (ACE) inhibitor, initially as mono-therapy, is the first choice antihypertensive agent in the absence of contraindications. Often dual or triple therapy is required to achieve target blood pressure levels.


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