Home About us Current issue Back issues Submission Instructions Advertise Contact Login   

Search Article 
  
Advanced search 
 
Saudi Journal of Kidney Diseases and Transplantation
Users online: 3376 Home Bookmark this page Print this page Email this page Small font sizeDefault font size Increase font size 


 
CASE REPORT Table of Contents   
Year : 2003  |  Volume : 14  |  Issue : 2  |  Page : 177-185
Unusual Presentations of Wegener's granulomatosis: Pitfalls in Early Diagnosis


Department of Medicine, Aga Khan University Hospital, Karachi, Pakistan

Correspondence Address:
Syed Mansoor Ahmed Shah
Department of Medicine, Aga Khan University Hospital, Stadium Road, PO Box 3500, Karachi – 74800
Pakistan
Login to access the Email id


PMID: 18209443

Rights and Permissions

Wegener's Granulomatosis (WG) is a disorder characterized by necrotizing granulomatous vasculitis that primarily affects the upper and lower respiratory tracts and the kidneys. Although the cause is unknown, there is strong evidence that this is an autoimmune disease and immunosuppressive therapy with cyclophosphamide and corticosteroids efficiently relieves the symptoms and, prevents relapses. We report on four cases of WG that presented with unusual features. The first patient presented with vague joint pain, blackish discoloration of the skin and leg ulcers. The second patient presented as fever of unknown origin and gingival hyperplasia. The third patient presented with hearing loss while the fourth presented with arthritis, conjunctivitis and painful swelling of the ear. It is emphasized that WG is a complex disease and can involve multiple organ systems. Early recognition and institution of proper treatment are crucial for optimal outcome.


[FULL TEXT] [PDF]*
Print this article  Email this article
    

  Similar in PUBMED
    Search Pubmed for
    Search in Google Scholar for
  Related articles
   Citation Manager
  Access Statistics
   Reader Comments
   Email Alert *
   Add to My List *
 * Requires registration (Free)
 

 Article Access Statistics
    Viewed5439    
    Printed85    
    Emailed0    
    PDF Downloaded416    
    Comments [Add]    

Recommend this journal