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Saudi Journal of Kidney Diseases and Transplantation
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CASE REPORT Table of Contents   
Year : 2007  |  Volume : 18  |  Issue : 1  |  Page : 95-99
Cerebral Salt Wasting in a Patient with Head Trauma: Management with Saline Hydration and Fludrocortisone


Department of Medicine, Division of Nephrology, King Khalid University Hospital, Riyadh, Saudi Arabia

Correspondence Address:
Nauman Tarif
Consultant Nephrologist, Department of Medicine King Khalid University Hospital, P.O. Box 2925 [38], Riyadh 11461
Saudi Arabia
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PMID: 17237900

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Hyponatremia secondary to the syndrome of inappropriate anti-diuretic hormone secretion is commonly observed in patients with various neurological disorders. Cerebral salt wasting (CSW), although uncommon, has also been reported to frequently result in hyponatremia. Here, we report a case of CSW in a patient with head trauma without evidence of cerebrovascular injury or brain edema. He was diagnosed on the basis of high fractional excretion of urinary sodium and uric acid along with extremely low serum uric acid. Improvements in serum sodium levels after saline hydration and fludrocortisone administration further supported the diagnosis, even in the presence of normal brain and atrial natriuretic peptide levels.


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