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Saudi Journal of Kidney Diseases and Transplantation
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ORIGINAL ARTICLE Table of Contents   
Year : 2007  |  Volume : 18  |  Issue : 4  |  Page : 556-564
Prevalence and Clinical Findings of Biopsy-Proven Glomerulonephritidis in Iran


1 Division of Nephrology, Isfahan University of Medical Sciences and Health Services, Isfahan, Iran
2 Division of Nephrology, Iran University of Medical Sciences and Health Services, Tehran, Iran
3 Division of Nephrology, Department of Internal Medicine, Saint Louis University Health Sciences Center, Saint Louis, Missouri, USA

Correspondence Address:
Afsoon Emami Naini
Department of Nephrology, Noor Hospital, Isfahan University of Medical Sciences, Isfahan
Iran
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PMID: 17951943

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Epidemiological data of renal diseases is population-based and have great geographic variability. Due to the lack of a national renal data registry system, there is no information on the prevalence rate, and clinical and laboratory features of various glomerulo­nephritidis (GNs) in Iran. In a retrospective cross sectional study, we analyzed 462 adult renal biopsies in Tehran, Iran. We determined the prevalence rate and the frequency of different clinical and laboratory findings in patients with different GNs. We also compared our results with the reports from other countries. There were 267 (57.8%) males and 195 (42.2%) females. The mean (± SD) age was 33.6 ± 15.7 (range, 13-75) years. A total of 55 biopsies, which had revealed pathologies other than GNs, were excluded. Among the remaining 407 biopsies, membranous glomerulopathy (MGN) was the most common GN (23.6%), followed by IgAN (13.5%), membranoproliferative GN (MPGN) (11.5%), systemic lupus nephritis (SLE-GN) (10.6%), focal and segmental glomerulosclerosis (FSGS) (10.3%), and minimal change disease (MCD) (9.8%). Our study shows that MGN is the most common form of GN, followed by IgAN, MPGN, SLE­GN, FSGS and MCD in adult patients in Iran. A multi-center study with a larger sample size is needed for more comprehensive data in Iranian population.


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