Home About us Current issue Back issues Submission Instructions Advertise Contact Login   

Search Article 
  
Advanced search 
 
Saudi Journal of Kidney Diseases and Transplantation
Users online: 776 Home Bookmark this page Print this page Email this page Small font sizeDefault font size Increase font size 


 
RENAL DATA FROM THE ASIA - AFRICA Table of Contents   
Year : 2008  |  Volume : 19  |  Issue : 3  |  Page : 470-474
Lupus Nephritis in Senegal: A Study of 42 Cases


1 Service de Nephrologie, Centre Hospitalier Universitaire Aristide Le Dantec de Dakar, Senegal
2 Service de Medecine Interne, Centre Hospitalier Universitaire Aristide Le Dantec de Dakar, Senegal
3 Service de Dermatologie, Centre Hospitalier Universitaire Aristide Le Dantec de Dakar, Senegal

Correspondence Address:
A Niang
B.P. 6548, Dakar Etoile, Dakar
Senegal
Login to access the Email id


PMID: 18445916

Rights and Permissions

Renal involvement determines the prognosis of systemic lupus erythematosus (SLE). The aims of this study were to assess the clinical, laboratory and therapeutic aspects of lupus nephritis (LN) in Senegal in order to improve its management. We included all patients presenting with SLE followed­up in the Internal Medicine and Dermatology Clinics of the Aristide Le Dantec University Teaching Hospital of Dakar, from January 1993 to December 2002. Patients with SLE without evidence of LN (defined by proteinuria more than 0.5 g/24 hours and/or hematuria) were excluded. A total of 74 patients with a diagnosis of SLE were studied, 42 of whom (56.75%) had features of LN. Their mean age was 29.6 years and male-female ratio was 0.13. The nephrotic syndrome was seen in 45.23% of the cases and renal insufficiency in 37.71%. Renal biopsy was performed in 52.38% of the cases, which showed predominantly WHO classes IV and V lesions. The main treatment modality employed was corticoste­roids, while immunosuppressive drugs in addition were used in 35.71% of the patients. The short-term prognosis was favorable but in the middle-term, many patients were lost to follow-up. We conclude that early diagnosis by systematic urine screening, good patient information, percutaneous renal biopsy and use of appropriate immunosuppressive therapy will help improving the prognosis of LN in Senegal.


[FULL TEXT] [PDF]*
Print this article  Email this article
    

  Similar in PUBMED
    Search Pubmed for
    Search in Google Scholar for
  Related articles
   Citation Manager
  Access Statistics
   Reader Comments
   Email Alert *
   Add to My List *
 * Requires registration (Free)
 

 Article Access Statistics
    Viewed3162    
    Printed86    
    Emailed0    
    PDF Downloaded514    
    Comments [Add]    
    Cited by others 5    

Recommend this journal