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Saudi Journal of Kidney Diseases and Transplantation
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SCOT FORUM Table of Contents   
Year : 2008  |  Volume : 19  |  Issue : 4  |  Page : 669-677
Dilemma of Renal Disease in Elderly


1 Nephrology Unit, New Damietta Al-Azhar University Hospital and Faculty of Medicine, Mansoura Urology and Nephrology Center, Mansoura, Egypt
2 Department of Nephrology, Armed Forces Hospital, Riyadh, Saudi Arabia

Correspondence Address:
Mohamed Al-Sulaiman
Department of Nephrology, Riyadh Armed Forces Hospital, Riyadh
Saudi Arabia
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PMID: 18580035

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The aging process results in profound anatomic and functional changes in a number of human body systems. Changes in kidney function with normal aging are the most dramatic of any human organ or organ system. These include anatomical, physiological, hemodynamic and immunological changes. Increased propensities of systemic diseases and exposure to poly-pharmacy of the aged group have an additive deleterious effect. The aforementioned changes have its implications on clinical presentations, management and prognosis of all renal diseases in elderly. Atypical presentation, more frequent and longer course are the characteristics of acute renal failure in this age group. Also, presentation of glomerular diseases, clinical course, prognosis, decision of performing a renal biopsy and use of immunosuppressive drugs in elderly specially those subgroup above 80 years of age are still a big challenges that needs a consensus and standardization.


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