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Saudi Journal of Kidney Diseases and Transplantation
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ORIGINAL ARTICLE Table of Contents   
Year : 2009  |  Volume : 20  |  Issue : 2  |  Page : 240-245
Risk score for contrast induced nephropathy following percutaneous coronary intervention


1 Nephrology Department, Mubarak Al Kabeer Hospital, Kuwait
2 Cardiology Department, Al- Sabah Hospital, Ministry of Health, Kuwait

Correspondence Address:
Amal Abdel Ghani
Nephrology Unit, Mubarak Al Kabeer Hospital, P.O. Box 43787, Code 3205 Hawally
Kuwait
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PMID: 19237811

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Contrast-induced nephropathy (CIN) is an important cause of acute renal failure. Identification of risk factors of CIN and creating a simple risk scoring for CIN after percutaneous coronary intervention (PCI) is important. A prospective single center study was conducted in Kuwait chest disease hospital. All patients admitted to chest disease hospital for PCI from March to May 2005 were included in the study. Total of 247 patients were randomly assigned for the development dataset and 100 for the validation set using the simple random method. The overall occurrence of CIN in the development set was 5.52%. Using multivariate analysis; basal Serum creatinine, shock, female gender, multivessel PCI, and diabetes mellitus were identified as risk factors. Scores assigned to different variables yielded basal creatinine > 115 µmol/L with the highest score(7), followed by shock (3), female gender, multivessel PCI and diabetes mellitus had the same score (2). Patients were further risk stratified into low risk score (< 4), moderate (5-8), high (9-12), and, very high risk score (>_ 12). The developed CIN model demonstrated good dis­criminative power in the validation population. In conclusion, use of a simple risk score for CIN can predict the probability of CIN after PCI; this however needs further validation in larger multi­center trials.


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