Home About us Current issue Back issues Submission Instructions Advertise Contact Login   

Search Article 
  
Advanced search 
 
Saudi Journal of Kidney Diseases and Transplantation
Users online: 1560 Home Bookmark this page Print this page Email this page Small font sizeDefault font size Increase font size 
 

LETTER TO THE EDITOR Table of Contents   
Year : 2009  |  Volume : 20  |  Issue : 3  |  Page : 481-482
CMV infection in post kidney transplant recipient


Department of Nephrology, Kanoo Kidney Centre, Dammam Medical Complex, P.O. Box 10387, Dammam 31433, Saudi Arabia

Click here for correspondence address and email
 

How to cite this article:
Abdelrahman M, Karkar A. CMV infection in post kidney transplant recipient. Saudi J Kidney Dis Transpl 2009;20:481-2

How to cite this URL:
Abdelrahman M, Karkar A. CMV infection in post kidney transplant recipient. Saudi J Kidney Dis Transpl [serial online] 2009 [cited 2020 Jun 6];20:481-2. Available from: http://www.sjkdt.org/text.asp?2009/20/3/481/50786
To the Editor,

Cytomegalovirus virus (CMV) infection and disease is the major infectious complication in renal allograft recipients, and is known as an independent risk factor for acute rejection and chronic allograft dysfunction. We describe primary CMV infection in a 55 year old male patient with end stage renal disease due to Diabetic nephropathy. The patient, who was CMV negative, received live unrelated renal transplant abroad from a positive CMV donor with full recovery of renal function. He was placed on cyclosporine, prednisolone, and mycophenolate mofetil, together with acyclo­vir and sulphamethoxazole/Trimethoprim. Six weeks after transplantation, he presented with fever, malaise, anorexia and cellulites of the right toe. Laboratory investigations showed leukopenia, minimally impaired liver function tests, and E. coli and  Pseudomonas aeruginosa Scientific Name Search re cultured from the right toe. Antibiotics were prescribed but his fever persisted. Con­sequently, he developed dysphagia, and re­testing for CMV IgM was positive (PCR was not available). Gastroscopy showed active chronic gastritis with esophageal inflammation and ulceration. Esophageal biopsy revealed features suggestive of herpes simplex and/or CMV infection [Figure 1] and [Figure 2]. The patient was started and maintained on gancyclovir intravenously for 3 weeks. Thereafter, he be­came afebrile, the dysphagia resolved, liver function tests became normal and CMV IgG became positive. We conclude that prophylactic treatment with gancyclovir is essential in renal transplant recipients especially in the D+/R­setting.

Top
Correspondence Address:
Mohammed Abdelrahman
Department of Nephrology, Kanoo Kidney Centre, Dammam Medical Complex, P.O. Box 10387, Dammam 31433
Saudi Arabia
Login to access the Email id


PMID: 19414958

Rights and Permissions


    Figures

  [Figure 1], [Figure 2]



 

Top
 
 
    Similar in PUBMED
    Search Pubmed for
    Search in Google Scholar for
    Email Alert *
    Add to My List *
* Registration required (free)  
 


 
    Article Figures
 

 Article Access Statistics
    Viewed2615    
    Printed65    
    Emailed0    
    PDF Downloaded567    
    Comments [Add]    

Recommend this journal