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Saudi Journal of Kidney Diseases and Transplantation
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CASE REPORT Table of Contents   
Year : 2010  |  Volume : 21  |  Issue : 5  |  Page : 940-942
Frank hematuria as the presentation feature of acute leukemia


1 Department of Accident and Emergency, King Khalid University Hospital, King Saud University, Riyadh, Saudi Arabia
2 Department of Medicine (Division of Hematology/Oncology), King Khalid University Hospital, King Saud University, Riyadh, Saudi Arabia

Correspondence Address:
Aamer Aleem
Associate Professor and Consultant Hematologist, Department of Medicine (38), King Khalid University Hospital, P.O. Box 7805, Riyadh 11461
Saudi Arabia
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PMID: 20814137

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Muco-cutaneous bleeding is a common presenting feature of acute leukemias. Mucosal bleeding usually manifests as gum bleeding and/or epistaxis but may occur in any mucosal surface of the body. Hematuria as an isolated or main presenting feature of acute leukemia is rare. We describe two cases of acute leukemia, a 19 year old male with acute lymphoblastic leukemia and a 52 year old male with acute myeloid leukemia, both presenting with gross hematuria. There was no demonstrable leukemic infiltration of the urinary tract on imaging studies. Hematuria in these patients was likely to be due to occult leukemic infiltration of the urinary system, aggravated by thrombocytopenia, as it subsided after starting chemotherapy. Our cases highlight that hematuria should be remembered as a rare presenting feature of acute leukemia.


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