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Saudi Journal of Kidney Diseases and Transplantation
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CASE REPORT Table of Contents   
Year : 2011  |  Volume : 22  |  Issue : 1  |  Page : 126-129
Collagenofibrotic glomerulopathy in association with hodgkin's lymphoma


1 Department of Nephrology, Mediciti Hospitals, Aurangabad, Maharashtra; Department of Nephrology, Manik Hospital and Research Centre, Aurangabad, India
2 Department of Histopathology, Apollo Health City, Hyderabad, Andhra Pradesh, India
3 Department of Nephrology, Mediciti Hospitals, Aurangabad, Maharashtra, India

Correspondence Address:
Anuradha Raman
Director of Nephrology, Mediciti Hospitals, 5-9-22, Secretariat Road, Hyderabad 500063, Andhra Pradesh
India
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PMID: 21196628

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Deposit glomerulopathies are characterized by fibrillary deposits of various sizes, mainly in the mesangial area. Collagenofibrotic glomerulopathy is a rare type of such fibrillary glomerulopathies characterized by deposits of 60-80 nm fibrils in the sub-endothelial and mesan­gial areas. It is also associated with increased levels of serum pro-collagen type III peptide (PIIINP). Although most of the initial reports have emanated from Japan, many other scientists around the globe have later reported this disease. Possibility of systemic disease affecting metabolism of type III collagen is postulated but so far no such association has been identified. We report a 26-year­old male patient who presented with insidious onset of febrile illness associated with lympha­denopathy and proteinuria. Lymph node biopsy revealed features of Hodgkin's lymphoma while percutaneous renal biopsy showed features of collagenofibrotic glomerulopathy.


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