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Saudi Journal of Kidney Diseases and Transplantation
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LETTER TO THE EDITOR  
Year : 2011  |  Volume : 22  |  Issue : 2  |  Page : 345-346
Renal biopsies in glomerular diseases


Department of Pathology, Shri B. M. Patil Medical College, Bijapur and KBNIMS, Gulbarga, India

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Date of Web Publication18-Mar-2011
 

How to cite this article:
Attar AH, Jadhav M N, Zeenath B, Madraki R M, Yelikar B R. Renal biopsies in glomerular diseases. Saudi J Kidney Dis Transpl 2011;22:345-6

How to cite this URL:
Attar AH, Jadhav M N, Zeenath B, Madraki R M, Yelikar B R. Renal biopsies in glomerular diseases. Saudi J Kidney Dis Transpl [serial online] 2011 [cited 2020 Jun 6];22:345-6. Available from: http://www.sjkdt.org/text.asp?2011/22/2/345/77629
To the Editor,

Renal biopsy is the corner stone for diagnosis of glomerular diseases, which not only pro­vides precise diagnosis, but also helps in the treatment and the assessment of the prognosis. Percutaneous gun biopsies have a higher diag­nostic yield with fewer complications. We stu­died the spectrum of glomerular diseases in our hospital from August 2005 to August 2007. We studied 40 renal biopsies using 18-Gauge "Bard's bioptic gun", and adequate tissue was obtained in 97.5% patients. The sections of the specimens were stained with hematoxylin and eosin; special stains and immunofluorescence were used whenever necessary. Focal segmen­tal glomerulosclerosis (FSGS) was most com­mon accounting for 25% of cases, followed by mesangioproliferative glomerulonephritis (GN) in 22.5% of cases. Among the secondary glo­merular diseases, amyloidosis accounted for 10% of cases. [Table 1] shows the distribution of the GN in our study patients.
Table 1: Incidence of primary and secondary glomerulonephritis (GN) in our study patients.

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It seems that the incidence of FSGS increased over the past two decades as reported else­where. [1],[2],[3],[4],[5],[6],[7],[8] Minimal change disease is common below the age of 10 years.

 
   References Top

1.Braden GL, Mulhern JG, O'Shea MH, Nash SV, Ucci AA Jr, Germain MJ. Changing inci­dence of glomerular diseases in adults. Am J Kidney Dis 2000;35(5):878-83.  Back to cited text no. 1
    
2.Lynn K. Familial focal and segmental glome­rulosclerosis. Indian J Nephrol 1999;4:130-4.  Back to cited text no. 2
    
3.Abrantes MM, Cardoso LS, Lima EM, et al. Clinical course of 110 children and adolescents with primary focal segmental glomeruloscle­rosis. Pediatr Nephol 2006;21:482-9.  Back to cited text no. 3
    
4.Rana K, Isbel N. Clinical, Histopathologic and Genetic studies in nine families with focal segmental glomerulosclerosis. Am J Kidney Dis 2003;4(6):1170-8.  Back to cited text no. 4
    
5.Schwartz MM, Korbet MS. Current concepts in renal pathology. Am J Kidney Dis 1993;22(6):874-83.  Back to cited text no. 5
    
6.Balakrishnan N, John GT, Korula A, et al. Spectrum of biopsy proven renal diseases and changing trends at a tropical tertiary care centre. Indian J Nephrol 2003;13:29-35.  Back to cited text no. 6
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7.Burstein MD, Korbet MS, Schwartz MM. The use of automatic core biopsy system in percu­taneous renal biopsies: A comparative study. Am J Kidney Dis 1993;22:545-52.  Back to cited text no. 7
    
8.Daskalakis N, Winn PM. Focal and segmental glomerulosclerosis: Varying biologic mecha­nisms underlie a final histopathologic end point. Semin Nephrol 2006;26:89-94.  Back to cited text no. 8
    

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Correspondence Address:
B Zeenath
Department of Pathology, Shri B. M. Patil Medical College, Bijapur and KBNIMS, Gulbarga
India
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PMID: 21422641

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