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Saudi Journal of Kidney Diseases and Transplantation
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Table of Contents   
LETTER TO THE EDITOR  
Year : 2011  |  Volume : 22  |  Issue : 5  |  Page : 1047
Author's Reply


Senior Registrar, Department of Nephrology, A-791, Lilavati Hospital and Research Centre, Bandra Reclamation, Bandra-West, Mumbai-400050, Maharashtra State, India

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Date of Web Publication6-Sep-2011
 

How to cite this article:
Malleshappa P. Author's Reply. Saudi J Kidney Dis Transpl 2011;22:1047

How to cite this URL:
Malleshappa P. Author's Reply. Saudi J Kidney Dis Transpl [serial online] 2011 [cited 2020 Jul 12];22:1047. Available from: http://www.sjkdt.org/text.asp?2011/22/5/1047/84568
To the Edito r,

On behalf of all the authors, we thank Dr. Muhammed Mubarak for his interest in our case study. We agree that C1q nephropathy has been reported in the past as rapidly progressive glomerulonephritis. We are also grateful to him for pointing out some oversights on our part. We agree that respiratory rate was wrongly written as beats per minute instead of breaths per minute. We totally agree that two complement fragments cannot be shown in one figure and the figure that we are depicting in our case report is the deposition of C1q. In addition, our patient had C3 deposits. There were no immunoglobulins seen in this biopsy. On light microscopy, in the glomeruli that showed proliferation, there were 4-5 mesangial cells, the remaining showed 2-3 cells per mesangial area. We also agree that electron microscopy is not the confirmatory test to diagnose C1q nephropathy and there were no tubuloreticular inclusions seen. It is the overall clinical history and histopathology in the absence of systemic lupus erythematosus (SLE) that lead us to the diagnosis of C1q nephropathy. Finally, the follow-up was short when we reported this case. Two years following the diagnosis of C1q nephropathy, the patient is now on prednisolone 5 mg/day with stable renal function (creatinine 1.5 mg/dL), no proteinuria, and without any seroconversion to SLE.

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Correspondence Address:
Pavan Malleshappa
Senior Registrar, Department of Nephrology, A-791, Lilavati Hospital and Research Centre, Bandra Reclamation, Bandra-West, Mumbai-400050, Maharashtra State
India
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