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Saudi Journal of Kidney Diseases and Transplantation
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Table of Contents   
LETTER TO THE EDITOR  
Year : 2012  |  Volume : 23  |  Issue : 2  |  Page : 367
Nanotechnology in nephrology


Department of Periodontology and Oral Implantology, Rural Dental College, Loni, Tehsil, Rahata, District Ahmednagar, Maharashtra, India

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Date of Web Publication28-Feb-2012
 

How to cite this article:
Saini R, Saini S, Saini SR. Nanotechnology in nephrology. Saudi J Kidney Dis Transpl 2012;23:367

How to cite this URL:
Saini R, Saini S, Saini SR. Nanotechnology in nephrology. Saudi J Kidney Dis Transpl [serial online] 2012 [cited 2014 Oct 25];23:367. Available from: http://www.sjkdt.org/text.asp?2012/23/2/367/93181
To the Editor ,

Nanotechnology can be defined as the science and engineering involved in the design, syn­thesis, characterization, and application of ma­terials and devices whose smallest functional organization, in at least one dimension, is on the nanometer scale or one billionth of a meter and the promise that nanotechnology brings is multifaceted, offering not only improvements to the current techniques, but also providing entirely new tools and capabilities. [1] Nano-nephrology is a branch of nanomedicine and nanotechnology that deals with the study of kidney protein structures at the atomic level, nanoimaging approaches to study cellular pro­cesses in kidney cells and novel medical treatments that utilize nanoparticles and to treat various kidney diseases. Nowadays, nano-technology and microfluidic technologies are emerging as enabling factors for the operation of lab-on-chip devices and micro total analysis systems in the biotechnological and biome-dical fields. These devices allow to reduce the waste of reagents and products, and to increase analytical precision and operational throughput. [2] The theoretical advantages of micro- and nano­meter scale engineering to renal replacement include the manufacture of high-hydraulic per­meability membranes with implanted sensing and control structures. Recent data in mem­brane design and testing is presented, with a review of the challenges remaining in imple­mentation of this technology. [3] Recently re­searchers have developed a human nephron filter (HNF) that would eventually make possible a continuously functioning, wearable or implantable artificial kidney. The HNF is the first application in developing a renal replace­ment therapy (RRT) to potentially eliminate the need for dialysis or kidney transplantation in end-stage renal disease patients. The HNF utilizes a unique membrane system created through applied nanotechnology. In the ideal RRT device, this technology would be used to mimic the function of natural kidneys, conti­nuously operating, and based on individual patient needs. The promise that nanotechno-logy brings is multifaceted, offering not only improvements to the current techniques, but also providing entirely new tools and capa­bilities.

 
   References Top

1.Saini R, Saini S, Sharma S. Nanotechnology: The future medicine. J Cutan Aesthet Surg 2010;3:32-3.  Back to cited text no. 1
[PUBMED]  Medknow Journal  
2.Pisignano D. Nanotechnology and nephrology. G Ital Nefrol 2007;40:80-6.  Back to cited text no. 2
    
3.Fissell WH, Humes HD, Fleischman AJ, Roy S. Dialysis and nanotechnology: Now, 10 years, or never. Blood Purif 2007;25:12-7.  Back to cited text no. 3
[PUBMED]  [FULLTEXT]  

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Correspondence Address:
Rajiv Saini
Department of Periodontology and Oral Implantology, Rural Dental College, Loni, Tehsil, Rahata, District Ahmednagar, Maharashtra
India
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PMID: 22382241

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