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Saudi Journal of Kidney Diseases and Transplantation
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LETTER TO THE EDITOR  
Year : 2013  |  Volume : 24  |  Issue : 5  |  Page : 1002
Authors Reply


Department of Pathology and Laboratory Medicine, King Abdulaziz Medical City, National Guard Health Affairs, Riyadh, Kingdom of Saudi Arabia

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Date of Web Publication12-Sep-2013
 

How to cite this article:
Hajeer AH. Authors Reply. Saudi J Kidney Dis Transpl 2013;24:1002

How to cite this URL:
Hajeer AH. Authors Reply. Saudi J Kidney Dis Transpl [serial online] 2013 [cited 2019 Nov 18];24:1002. Available from: http://www.sjkdt.org/text.asp?2013/24/5/1002/118072
To the Editor ,

We agree with Vasco et al on the importance of HLA-C molecular typing and its role in bone marrow transplantation. Our article [1] raised the issue of molecular versus serology typing and how molecular typing revealed the true HLA-C allele distribution in the Saudi population. Currently, we have the technology to identify with good sensitivity and specificity donor-specific PRA antibodies. In solid organ transplantation, having the full typing of the donor allows the identification of donor versus non-donor-specific PRA. Vasco et al suggested that molecular typing of HLA-C plays an important role in unrelated stem cell donor matching. We have recently established the first Arabic registry for unrelated stem cell donors. We are typing donors for HLA-A, B, C, DRB1 and DQB1 using a sequence-based typing method. This will help in finding unrelated donors who are 10/10 match.

 
   References Top

1.Jawdat D, Al Saleh S, Sutton P, et al. HLA-C polymorphisms in two cohorts of donors for bone marrow transplantation. Saudi J Kidney Dis Transpl 2012;23:467-70.  Back to cited text no. 1
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Correspondence Address:
Ali H Hajeer
Department of Pathology and Laboratory Medicine, King Abdulaziz Medical City, National Guard Health Affairs, Riyadh
Kingdom of Saudi Arabia
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DOI: 10.4103/1319-2442.118072

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