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Saudi Journal of Kidney Diseases and Transplantation
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Table of Contents   
LETTER TO THE EDITOR  
Year : 2017  |  Volume : 28  |  Issue : 3  |  Page : 666
New-onset diabetes after kidney transplantation and the role of cytomegalovirus


Nephrology and Urology Research Center, Baqiyatallah University of Medical Sciences, Tehran, Iran

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Date of Web Publication18-May-2017
 

How to cite this article:
Lotfiazar A, Einollahi B, Zijoud SM, Shahyad S. New-onset diabetes after kidney transplantation and the role of cytomegalovirus. Saudi J Kidney Dis Transpl 2017;28:666

How to cite this URL:
Lotfiazar A, Einollahi B, Zijoud SM, Shahyad S. New-onset diabetes after kidney transplantation and the role of cytomegalovirus. Saudi J Kidney Dis Transpl [serial online] 2017 [cited 2020 Feb 28];28:666. Available from: http://www.sjkdt.org/text.asp?2017/28/3/666/206467
To the Editor,

We read with interest the article entitled, “New- onset Diabetes after Kidney Transplantation: Incidence, Risk Factors, and Outcomes” which was published in your valuable journal. Aleid et al evaluated the incidence, risk factors, and outcomes of the New-onset Diabetes after Kidney Transplantation (NODAT) among 500 kidney transplant patients between 2003 and 2009.[1]

In this study, Aleid et al showed that advanced age, obesity, positive history of diabetes, hepatitis C infection, impaired fasting glucose, and impaired glucose tolerance were risk factors for NODAT in renal transplant recipients.[1]

In addition, some other studies have revealed the impact of cytomegalovirus (CMV) infection on NODAT.[2] In a meta-analysis study, we also found that the risk of NODAT among CMV-infected transplant patients was 1.96-fold than the control group.[3] Moreover, Hjelmesaeth et al also found higher risk for NODAT (4fold than controls) in patients with CMV infection.[4]

Thus, we should evaluate all transplant patients with NODAT for the presence of CMV infection. It is obvious that CMV infection is an important complication after kidney transplantation and determination of this serious infection as a risk factor of NODAT could be life-saving issue.

Conflict of interest: None declared.

 
   References Top

1.
Aleid H, Alhuraiji A, Alqaraawi A, et al. New- onset diabetes after kidney transplantation: Incidence, risk factors, and outcomes. Saudi J Kidney Dis Transpl 2016;27:1155-61.  Back to cited text no. 1
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2.
Chow KM, Li PK. Review article: New-onset diabetes after transplantation. Nephrology (Carlton) 2008;13:737-44.  Back to cited text no. 2
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3.
Einollahi B, Motalebi M, Salesi M, Ebrahimi M, Taghipour M. The impact of cytomegalo- virus infection on new-onset diabetes mellitus after kidney transplantation: A review on current findings. J Nephropathol 2014;3:139- 48.  Back to cited text no. 3
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4.
Hjelmesaeth J, Sagedal S, Hartmann A, et al. Asymptomatic cytomegalovirus infection is associated with increased risk of new-onset diabetes mellitus and impaired insulin release after renal transplantation. Diabetologia 2004; 47:1550-6.  Back to cited text no. 4
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Correspondence Address:
Dr. Aidin Lotfiazar
Nephrology and Urology Research Center, Baqiyatallah University of Medical Sciences, Tehran
Iran
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DOI: 10.4103/1319-2442.206467

PMID: 28540913

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