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Saudi Journal of Kidney Diseases and Transplantation
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LETTER TO THE EDITOR  
Year : 2017  |  Volume : 28  |  Issue : 4  |  Page : 947
Solid organ transplantation and zika virus infection


1 KMT Primary Care Center, Bangkok, Thailand
2 Visiting Professor, Hainan Medical University, China

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Date of Web Publication21-Jul-2017
 

How to cite this article:
Yasri S, Wiwanitkit V. Solid organ transplantation and zika virus infection. Saudi J Kidney Dis Transpl 2017;28:947

How to cite this URL:
Yasri S, Wiwanitkit V. Solid organ transplantation and zika virus infection. Saudi J Kidney Dis Transpl [serial online] 2017 [cited 2020 Aug 3];28:947. Available from: http://www.sjkdt.org/text.asp?2017/28/4/947/211352


To the Editor,

The Zika virus infection is currently a big global medical problem. This infection can cause several complications including severe neurological disturbance. Initially, the Zika virus infection was believed to be a vectorborne disease. Nevertheless, accumulated data show that there are other modes of transmission including transmission by sexual contact, by blood transfusion and transplacental transmission.[1] Focusing on organ transplantation, the possibility of transmission of the Zika virus by solid organs has become a big concern in transplantation medicine.[2] According to a recent report by Grischott et al, based on the existing clinical evidences, the conclusion was that transplantation was not a mode of Zika virus transmission.[1] Nevertheless, it does not mean that there is no opportunity.[3] Focusing on the similar virus infection, dengue, organ transplantation is already proved to be an atypical mode of transmission.

Nevertheless, there are case reports already reported on Zika virus infection in organ transplant recipients.[2] However, blood transfusion during the organ transplantation process can be the cause of virus transmission. In addition, as cases of dengue virus, the other concern is the possibility that the patients might get the infection from other means such as mosquito bite during or posttransplantation.[5] Whether the virus can infect an organ and further cause transmission has never been proved. Further studies on this issue are necessary. It may be wise to implement Zika virus screening of blood and blood products as well as donated organs that might be the cause of transmission. In addition, the control of mosquitos in the hospital setting should also be addressed.[6]

Conflict of interest: None declared.



 
   References Top

1.
Grischott F, Puhan M, Hatz C, Schlagenhauf P. Non-vector-borne transmission of Zika virus: A systematic review. Travel Med Infect Dis 2016; 14:313-30.  Back to cited text no. 1
[PUBMED]    
2.
Nogueira ML, Estofolete CF, Terzian AC, et al. Zika virus infection and solid organ transplantation: A new challenge. Am J Transplant 2017; 17:791-5.  Back to cited text no. 2
[PUBMED]    
3.
Blumberg EA, Fishman JA. Zika virus in transplantation: Emerging infection and opportunities. Am J Transplant 2017;17:599-600.  Back to cited text no. 3
[PUBMED]    
4.
Gupta RK, Gupta G, Chorasiya VK, Bag P, Shandil R, Bhatia V, et al. Dengue virus transmission from living donor to recipient in liver transplantation: A case report. J Clin Exp Hepatol 2016;6:59-61.  Back to cited text no. 4
[PUBMED]    
5.
Joob B, Wiwanitkit V. Dengue transmission via transplantation: Need further evidence. Saudi J Kidney Dis Transpl 2014;25:152.  Back to cited text no. 5
[PUBMED]  [Full text]  
6.
Wiwanitkit V. Aedes mosquito larva in the hospital: A note from Thailand. Infect Control Hosp Epidemiol 2016;37:1519.  Back to cited text no. 6
    

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Correspondence Address:
Sora Yasri
KMT Primary Care Center, Bangkok
Thailand
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PMID: 28748906

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