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Saudi Journal of Kidney Diseases and Transplantation
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LETTER TO THE EDITOR  
Year : 2018  |  Volume : 29  |  Issue : 6  |  Page : 1518
Magnitude of renal problem in fatal cases of Lassa fever: A summary on existed reports


1 KMT Primary Care Center, Bangkok, Thailand
2 Department of Biological Science, Joseph Ayo Babalola University, Ilara-Mokin, Nigeria

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Date of Submission23-Mar-2018
Date of Acceptance29-Mar-2018
Date of Web Publication27-Dec-2018
 

How to cite this article:
Yasri S, Wiwanitkit V. Magnitude of renal problem in fatal cases of Lassa fever: A summary on existed reports. Saudi J Kidney Dis Transpl 2018;29:1518

How to cite this URL:
Yasri S, Wiwanitkit V. Magnitude of renal problem in fatal cases of Lassa fever: A summary on existed reports. Saudi J Kidney Dis Transpl [serial online] 2018 [cited 2019 Jun 18];29:1518. Available from: http://www.sjkdt.org/text.asp?2018/29/6/1518/248319
To the Editor,

The Lassa fever is an important emerging public health problem in Africa at present (2018). There is a possibility of a wide epidemic. The disease can result in hemorrhagic fever with a high mortality rate. Renal involvement is possible and not uncommon. Here, the authors try to summarize the magnitude of renal problem in Lassa fever based on the existed data in the previous reports. According to the literature, there are at least two reports on renal pathology in 27 fatal cases of Lassa fever.[3],[4] The renal pathology could be detected in all cases. The observed pathological findings include tubular necrosis, glomerular sclerosis, and interstitial nephritis, but there is no observation on ischemic pathology. For viral isolation, virus was detected in eight cases. Conclusively, the renal pathology is very common in the death cases of Lassa fever.

Conflict of interest: None declared.

 
   References Top

1.
Burki T. Lassa fever in Nigeria: The great unknown. Lancet 2018:391:728.  Back to cited text no. 1
    
2.
Okokhere P, Colubri A, Azubike C, et al. Clinical and laboratory predictors of Lassa fever outcome in a dedicated treatment facility in Nigeria: A retrospective, observational cohort study. Lancet Infect Dis 2018:18:684-95.  Back to cited text no. 2
    
3.
Winn WC Jr., Walker DH. The pathology of human Lassa fever. Bull World Health Organ 1975:52:535-45.  Back to cited text no. 3
    
4.
Walker DH, McCormick JB, Johnson KM, et al. Pathologic and virologic study of fatal Lassa fever in man. Am J Pathol 1982:107: 349-56.  Back to cited text no. 4
    

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Correspondence Address:
Dr. Sora Yasri
KMT Primary Care Center, Bangkok
Thailand
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DOI: 10.4103/1319-2442.248319

PMID: 30588991

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