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Saudi Journal of Kidney Diseases and Transplantation
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CASE REPORT Table of Contents   
Year : 2019  |  Volume : 30  |  Issue : 2  |  Page : 526-530
Biopsy-proven progressive multifocal leukoencephalopathy in a renal transplant patient


1 Department of Critical Care Medicine, Mayo Clinic, Florida, USA
2 Department of Dermatology, Mayo Clinic, Florida, USA
3 Department of Laboratory Medicine and Pathology, Mayo Clinic, Florida, USA

Correspondence Address:
Pramod Kumar Guru
Department of Critical Care Medicine, Mayo Clinic, Florida
USA
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DOI: 10.4103/1319-2442.256862

PMID: 31031391

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Progressive multifocal leukoencephalopathy (PML) is a rare demyelinating disease that affects immunocompromised hosts. Most often the disease is reported in association with leukemia, lymphoma, and AIDS. With recent advancements in immunosuppressive medications and subsequent rise in solid organ transplantations, it is becoming more prevalent in this population. Both the diagnosis and treatment of PML remains a challenge to the transplant community. The disease remains mostly underreported and undertreated. The diagnostic uncertainty in a renal transplant patient leads us to do the brain biopsy for suspicion and confirmation of PML.


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