Home About us Current issue Back issues Submission Instructions Advertise Contact Login   

Search Article 
  
Advanced search 
 
Saudi Journal of Kidney Diseases and Transplantation
Users online: 1111 Home Bookmark this page Print this page Email this page Small font sizeDefault font size Increase font size 

ORIGINAL ARTICLE Table of Contents   
Year : 2020  |  Volume : 31  |  Issue : 1  |  Page : 129-135
Metabolic syndrome, malnutrition, and its associations with cardiovascular and all-cause mortality in hemodialysis patients: Follow-up for three years


1 Department of Hemodialysis, Tahar Sfar Hospital, Mahdia; Faculty of Medicine, Monastir University, Monastir, Tunisia
2 Department of Biochemistry, Tahar Sfar Hospital, Mahdia, Tunisia
3 Faculty of Medicine, Tunis, Tunisia
4 Department of Urology, Tahar Sfar Hospital, Mahdia, Tunisia
5 Department of Hemodialysis; Department of Endocrinology, Tahar Sfar Hospital, Mahdia, Tunisia
6 Université Lille, INSERM U908, Cell Plasticity and Cancer, Lille, France

Correspondence Address:
Zohra El Ati
Department of Hemodialysis, Tahar Sfar Hospital, Mahdia
Tunisia
Login to access the Email id


DOI: 10.4103/1319-2442.279932

PMID: 32129205

Rights and Permissions

Metabolic disorder contributes to the increase in the mortality rate of patients on hemodialysis (HD). The aim of this study was to estimate the prevalence of metabolic syndrome (MS) and malnutrition in patients on maintenance HD and to evaluate their influence on cardiovascular and all-cause mortality during the follow-up. We carried out a prospective cross- sectional study in which we enrolled 100 patients from a single center who had been followed up for three years. Collected data included demographic characteristics, detailed medical history, clinical variables, MS variables, nutritional status, and laboratory findings. The outcomes were the occurrence of a cardiovascular event and cardiovascular or all-cause mortality during the follow-up period. The Statistical Package for the Social Sciences software was used for statistical analysis. Whereas 50% of patients had MS, 23% showed evidence of malnutrition. Patients with MS were older and had more preexisting cardiovascular diseases (CVDs). All patients were followed for 36 months. During this time, 19 patients with MS and 14 patients without MS died (38% vs. 28%; P = 0.19), most frequently of CVD. Mean survival time was 71.52 ± 42.1 months for MS group versus 92.06 ± 65 months for non-MS group, but the difference was not significant. MS was related with a higher cardiovascular mortality, while malnutrition was significantly associated with all-cause mortality. Our data showed that MS was not related to cardiovascular or all-cause mortality in HD patients and did not influence survival. The independent risk factors for all-cause mortality were older age, preexisting CVD, and malnutrition.


[FULL TEXT] [PDF]*
Print this article  Email this article
    

  Similar in PUBMED
    Search Pubmed for
    Search in Google Scholar for
   Citation Manager
  Access Statistics
   Reader Comments
   Email Alert *
   Add to My List *
 * Requires registration (Free)
 

 Article Access Statistics
    Viewed195    
    Printed1    
    Emailed0    
    PDF Downloaded37    
    Comments [Add]    

Recommend this journal