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Saudi Journal of Kidney Diseases and Transplantation
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CASE REPORT Table of Contents   
Year : 2020  |  Volume : 31  |  Issue : 4  |  Page : 856-859
Granulomatous Interstitial Nephritis Due to Renal-limited Sarcoidosis


1 Medical Student, King Saud University, Riyadh, Saudi Arabia
2 Department of Medicine, King Abdulaziz Medical City; King Saud Bin Abdulaziz University of Health Sciences; King Abdullah International Medical Research Center, Riyadh, Saudi Arabia
3 Department of Medicine, King Abdulaziz Medical City, Riyadh, Saudi Arabia
4 Department of Pathology, King Abdulaziz Medical City, Riyadh, Saudi Arabia

Correspondence Address:
Salih A Binsalih
Department of Medicine, King Abdulaziz Medical City, P. O. Box 22490, Mail code 1443, Riyadh 11426
Saudi Arabia
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DOI: 10.4103/1319-2442.292321

PMID: 32801248

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Sarcoidosis can present as acute kidney injury (AKI) due to granulomatous interstitial nephritis (GIN). AKI caused by sarcoid GIN without extra-renal manifestations is extremely rare. We report a case of a 42-year-old man with a history of unexplained weight loss admitted with progressively worsening kidney function. Physical examination did not show any abnormality. Laboratory investigations were normal except for high calcium level with no evidence of organ involvement of sarcoidosis. A renal biopsy showed GIN with non-caseating granulomata. Prednisolone was initiated and renal function improved. This is a case of an extremely rare AKI caused by sarcoid GIN without extra-renal manifestations which responded to prednisolone.


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