Saudi Journal of Kidney Diseases and Transplantation

CASE REPORT
Year
: 1995  |  Volume : 6  |  Issue : 2  |  Page : 206--210

Progression of Hepatitis C Infection in a Renal Transplant Recipient: A Case Report


Abdalla H Abdalla, Dujana H Mousa, Zalmai Rassoul, Fahad Al Hawas, Mohamed H Al Sulaiman, Abdullah A Al-Khader 
 Department of Nephrology, Riyadh Armed Forces Hospital, Riyadh, Saudi Arabia

Correspondence Address:
Abdalla H Abdalla
Department of Renal Medicine, Riyadh Armed Forces Hospital P.O. Box 7897, Riyadh 11159
Saudi Arabia

We present a patient with hepatitis C virus (HCV) infection who developed chronic active hepatitis (CAH) after renal transplantation. Alpha-interferon (a-IF) therapy was administered in view of deteriorating liver biochemistry. Liver histology at this stage showed features suggestive of chronic active hepatitis (CAH). The patient had stable graft function. Therapy with a-IF resulted in noticeable biochemical response within two weeks of commencement. An episode of steroid resistant renal allograft rejection occurred after 10 weeks of a-IF therapy which responded well to anti-lymphocyte globulin. Since then, the CAH has gradually progressed on to the development of cirrhotic changes and hepato-cellular carcinoma after 10 years following transplantation. Our case indicates that liver disease in anti­HCV positive patients can follow a serious course following renal transplantation.


How to cite this article:
Abdalla AH, Mousa DH, Rassoul Z, Al Hawas F, Al Sulaiman MH, Al-Khader AA. Progression of Hepatitis C Infection in a Renal Transplant Recipient: A Case Report.Saudi J Kidney Dis Transpl 1995;6:206-210


How to cite this URL:
Abdalla AH, Mousa DH, Rassoul Z, Al Hawas F, Al Sulaiman MH, Al-Khader AA. Progression of Hepatitis C Infection in a Renal Transplant Recipient: A Case Report. Saudi J Kidney Dis Transpl [serial online] 1995 [cited 2020 Apr 5 ];6:206-210
Available from: http://www.sjkdt.org/article.asp?issn=1319-2442;year=1995;volume=6;issue=2;spage=206;epage=210;aulast=Abdalla;type=0