Saudi Journal of Kidney Diseases and Transplantation

ORIGINAL ARTICLE
Year
: 2008  |  Volume : 19  |  Issue : 1  |  Page : 72--75

Outcome of Kidney Transplantation in Patients with Polycystic Kidney Disease: A Single Center Study


Jamshid Roozbeh, Ali Reza Razmkon, Hamed Jalaeian, Ganbar Ali Raiss-Jalali, Saeed Behzadi, Mohammad Mehdi Sagheb, Heshmatollah Salahi, Ali Bahador, Saman Nikeghbalian, Hamid Reza Davari, Mehdi Salehipour, Seyed Ali Malek-Hosseini 
 Shiraz Organ Transplant Center, Namazee Hospital, Shiraz University of Medical Sciences, Shiraz, Iran

Correspondence Address:
Jamshid Roozbeh
Associate Professor of Nephrology, Namazee Hospital, Shiraz University of Medical Sciences, Shiraz
Iran

Autosomal dominant polycystic kidney disease (ADPKD) is a common cause of end­stage renal disease and a common indication for renal transplantation. Patients with ADPKD show some differences in graft outcome and complications following renal transplantation. This study was undertaken to evaluate the demographics, outcome and complications of renal transplantation in patients with ADPKD. In a retrospective case-control design, 51 patients with ADPKD were recognized amongst a total of 1200 renal transplant patients. For each case, a matched control based on sex, age (± 5 years) and type of kidney donor, was selected. All relevant data were gathered using patients«SQ» records and PNOT software. There were 34 males (66.7%) and 17 females (33.3%) with ADPKD. Mean age at transplantation was 42.6 ± 14.3 years and source of donor organ was predominantly live unrelated (72.5%). Forty patients (78.4%) had extra-renal manifestations of ADPKD, the most common of which were cardiac valvular disease (24 cases, 47.1%), and liver cysts (10 cases, 19.6%). Rejection occurred in 12 patients in the case-group (23.5%) in comparison to nine patients (17.6%) in the control group (p > 0.05). Twenty-nine cases (56.9%) did not develop any complications. The common complications noted after transplantation included infections (15.7% in cases vs 19.6% in controls), and cerebrovascular accidents (13.7% in cases vs 16.6% in controls). Patient outcome after short- and long-term follow-up was slightly better in the ADPKD population than the control group; however, it was not statistically significant. Also, no complication was found to occur more frequently in ADPKD patients.


How to cite this article:
Roozbeh J, Razmkon AR, Jalaeian H, Raiss-Jalali GA, Behzadi S, Sagheb MM, Salahi H, Bahador A, Nikeghbalian S, Davari HR, Salehipour M, Malek-Hosseini SA. Outcome of Kidney Transplantation in Patients with Polycystic Kidney Disease: A Single Center Study.Saudi J Kidney Dis Transpl 2008;19:72-75


How to cite this URL:
Roozbeh J, Razmkon AR, Jalaeian H, Raiss-Jalali GA, Behzadi S, Sagheb MM, Salahi H, Bahador A, Nikeghbalian S, Davari HR, Salehipour M, Malek-Hosseini SA. Outcome of Kidney Transplantation in Patients with Polycystic Kidney Disease: A Single Center Study. Saudi J Kidney Dis Transpl [serial online] 2008 [cited 2019 Aug 17 ];19:72-75
Available from: http://www.sjkdt.org/article.asp?issn=1319-2442;year=2008;volume=19;issue=1;spage=72;epage=75;aulast=Roozbeh;type=0