Saudi Journal of Kidney Diseases and Transplantation

RENAL DATA FROM THE ASIA - AFRICA
Year
: 2010  |  Volume : 21  |  Issue : 2  |  Page : 368--371

Hematological profile of chronic kidney disease (CKD) patients in Iran, in pre-dialysis stages and after initiation of hemodialysis


Reza Afshar1, Suzan Sanavi1, Javad Salimi2, Mahnaz Ahmadzadeh1 
1 Nephrology Department, Shahed University, Mustafa Khomeini Hospital, Tehran, Iran
2 Vascular Surgery Department, Tehran University of Medical Sciences, Tehran, Iran

Correspondence Address:
Suzan Sanavi
Nephrology Department Mustafa Khomeini Hospital, Italia St, Tehran 1416645185
Iran

Anemia is a common sequealae of chronic kidney disease (CKD), associated with significant morbidity. A cross-sectional study was conducted on 100 CKD patients (54 hemodia­lyzed, 46 pre-dialyzed). Data including, complete blood count, BUN, creatinine, creatinine clea­rance, underlying diseases and hemodialysis duration were collected by a questionnaire. The most frequent morphologic features were normochromic-normocytic (80%), hypochromic-microcytic (15%) and macrocytic (5%). The frequency of anemia in hemodialyzed and pre-dialyzed patients (with mean Hgb level of 10.27 and 11.11 g/dL) were 85% and 75%. Hemoglobin concentration was positively correlated to calculated creatinine clearance (P < 0.001). The severity of anemia among hemodialyzed patients was mild (Hgb > 10 g/dL) in 5%, moderate in 70% and severe (Hgb < 7 g/dL) in 25%, while in pre-dialyzed was mild in 45% and moderate in 55%. There was no correlation between the anemia and CKD causes or hemodialysis duration. In conclusion, data shows that anemia in our patients with CKD is a predominant manifestation, with high frequency but of moderate degree. The most likely cause is inadequate erythropoietin production.


How to cite this article:
Afshar R, Sanavi S, Salimi J, Ahmadzadeh M. Hematological profile of chronic kidney disease (CKD) patients in Iran, in pre-dialysis stages and after initiation of hemodialysis.Saudi J Kidney Dis Transpl 2010;21:368-371


How to cite this URL:
Afshar R, Sanavi S, Salimi J, Ahmadzadeh M. Hematological profile of chronic kidney disease (CKD) patients in Iran, in pre-dialysis stages and after initiation of hemodialysis. Saudi J Kidney Dis Transpl [serial online] 2010 [cited 2020 Jul 13 ];21:368-371
Available from: http://www.sjkdt.org/article.asp?issn=1319-2442;year=2010;volume=21;issue=2;spage=368;epage=371;aulast=Afshar;type=0