Saudi Journal of Kidney Diseases and Transplantation

CASE REPORT
Year
: 2010  |  Volume : 21  |  Issue : 3  |  Page : 521--525

Transient IgA nephropathy with acute kidney injury in a patient with dengue fever


Bala Krishna Upadhaya1, Alok Sharma2, Ambar Khaira1, Amit K Dinda2, Sanjay K Agarwal1, Suresh C Tiwari1 
1 Department of Nephrology, All India Institute of Medical Sciences, New Delhi, India
2 Department of Pathology, All India Institute of Medical Sciences, New Delhi, India

Correspondence Address:
Amit K Dinda
Department of Pathology, All India Institute of Medical Sciences, New Delhi
India

Dengue virus infection can clinically manifest as dengue fever, dengue shock syn­drome and dengue hemorrhagic fever. Acute kidney injury as a result of dengue virus infection can occur due to various reasons including hypotension, rhabdomyolysis, sepsis and rarely immune complex mediated glomerular injury. However, glomerulonephritis associated with IgA Nephropathy in dengue virus infection has not been reported previously. We report a case of 15­year-old boy who was admitted with dengue fever and dialysis dependant acute kidney injury. Urine examination showed microscopic glomerular hematuria and proteinuria. Kidney biopsy showed mesangial proliferation with mesangial IgA dominant immune complex deposits and acute tubular necrosis. A repeated kidney biopsy 6 weeks after clinical recovery showed reversal of glomerular changes as well as resolution of mesangial IgA deposits.


How to cite this article:
Upadhaya BK, Sharma A, Khaira A, Dinda AK, Agarwal SK, Tiwari SC. Transient IgA nephropathy with acute kidney injury in a patient with dengue fever.Saudi J Kidney Dis Transpl 2010;21:521-525


How to cite this URL:
Upadhaya BK, Sharma A, Khaira A, Dinda AK, Agarwal SK, Tiwari SC. Transient IgA nephropathy with acute kidney injury in a patient with dengue fever. Saudi J Kidney Dis Transpl [serial online] 2010 [cited 2020 Jul 7 ];21:521-525
Available from: http://www.sjkdt.org/article.asp?issn=1319-2442;year=2010;volume=21;issue=3;spage=521;epage=525;aulast=Upadhaya;type=0