Saudi Journal of Kidney Diseases and Transplantation

ORIGINAL ARTICLE
Year
: 2011  |  Volume : 22  |  Issue : 4  |  Page : 705--711

Artificial neural network for prediction of equilibrated dialysis dose without intradialytic sample


Ahmad Taher Azar1, Khaled M Wahba2 
1 Electrical Communication & Electronics Systems Engineering department, Modern Science and Arts University (MSA), 6th of October City, Egypt
2 Systems and Biomedical Engineering Department, Faculty of Engineering, Cairo University, Egypt

Correspondence Address:
Ahmad Taher Azar
Menoufeya, Menouf, Ahmad Orabi Square, Azar Building
Egypt

Post-dialysis urea rebound (PDUR) is a cause of Kt/V overestimation when it is calculated from pre-dialysis and the immediate post-dialysis blood urea collections. Measuring PDUR requires a 30-or 60-min post-dialysis sampling, which is inconvenient. In this study, a supervised neural network was proposed to predict the equilibrated urea (C eq) at 60 min after the end of hemodialysis (HD). Data of 150 patients from a dialysis unit were analyzed. C eq was measured 60 min after each HD session to calculate PDUR, equilibrated urea reduction rate eq (URR), and ( eq Kt/V). The mean percentage of true urea rebound measured after 60 min of HD session was 19.6 ± 10.7. The mean urea rebound observed from the artificial neural network (ANN) was 18.6 ± 13.9%, while the means were 24.8 ± 14.1% and 21.3 ± 3.49% using Smye and Daugirdas methods, respectively. The ANN model achieved a correlation coefficient of 0.97 (P <0.0001), while the Smye and Daugirdas methods yielded R = 0.81 and 0.93, respectively (P <0.0001); the errors of the Smye method were larger than those of the other methods and resulted in a considerable bias in all cases, while the predictive accuracy for ( eq Kt/V) 60 was equally good by the Daugirdas«SQ» formula and the ANN . We conclude that the use of the ANN urea estimation yields accurate results when used to calculate ( eq Kt/V).


How to cite this article:
Azar AT, Wahba KM. Artificial neural network for prediction of equilibrated dialysis dose without intradialytic sample.Saudi J Kidney Dis Transpl 2011;22:705-711


How to cite this URL:
Azar AT, Wahba KM. Artificial neural network for prediction of equilibrated dialysis dose without intradialytic sample. Saudi J Kidney Dis Transpl [serial online] 2011 [cited 2019 Aug 23 ];22:705-711
Available from: http://www.sjkdt.org/article.asp?issn=1319-2442;year=2011;volume=22;issue=4;spage=705;epage=711;aulast=Azar;type=0