Saudi Journal of Kidney Diseases and Transplantation

ORIGINAL ARTICLE
Year
: 2011  |  Volume : 22  |  Issue : 4  |  Page : 727--732

Poor prognostic factors of lupus nephritis


Khawla Kammoun1, Faigal Jarraya1, Lamia Bouhamed1, Mahmoud Kharrat1, Saloua Makni2, Mohamed Ben Hmida1, Hafedh Makni3, Neila Kaddour4, Tahia Boudawara3, Zouhir Bahloul4, Jamil Hachicha1 
1 Department of Nephrology, Hedi Chaker Hospital, Sfax, Tunisia
2 Department of Immunology, Hedi Chaker Hospital, Sfax, Tunisia
3 Anatomopathology Department, Habib Bourguiba Hospital, Sfax, Tunisia
4 Department of Internal Medicine, Hedi Chaker Hospital, Sfax, Tunisia

Correspondence Address:
Khawla Kammoun
Nephrology Department, Hedi Chaker Hospital, Rout El Ain Km 1, Sfax
Tunisia

The occurrence of renal involvement during the clinical course of systemic lupus erythematous (SLE) is generally considered to be the most important factor influencing the prognosis in terms of morbidity and mortality. The factors influencing prognosis in lupus nephritis (LN) are variable in literature. Our aim was to determine predictive factors of poor prognosis in LN among our population. In this retrospective study, 82 cases of LN observed over 18 years were studied. There were 12 males and 70 females with a mean age of 26.9 ± 11 years. At presentation, the mean proteinuria was 3.9 ± 4 g/day; the nephrotic syndrome, hematuria, leukocyturia and renal failure were observed in 67.1%, 63.4%, 56.1% and 37.8% of cases, respectively. LN was of class I, II, III, IV and V in 4.9%, 13.4%, 23.2%, 50% and 8.5% of the cases, respectively. Fifteen patients developed end-stage renal failure and/or died. The presence of hypertension, renal failure, massive proteinuria and high activity index score of LN was associated with poor renal prognosis.


How to cite this article:
Kammoun K, Jarraya F, Bouhamed L, Kharrat M, Makni S, Hmida MB, Makni H, Kaddour N, Boudawara T, Bahloul Z, Hachicha J. Poor prognostic factors of lupus nephritis.Saudi J Kidney Dis Transpl 2011;22:727-732


How to cite this URL:
Kammoun K, Jarraya F, Bouhamed L, Kharrat M, Makni S, Hmida MB, Makni H, Kaddour N, Boudawara T, Bahloul Z, Hachicha J. Poor prognostic factors of lupus nephritis. Saudi J Kidney Dis Transpl [serial online] 2011 [cited 2020 Sep 20 ];22:727-732
Available from: http://www.sjkdt.org/article.asp?issn=1319-2442;year=2011;volume=22;issue=4;spage=727;epage=732;aulast=Kammoun;type=0