Saudi Journal of Kidney Diseases and Transplantation

CASE REPORT
Year
: 2016  |  Volume : 27  |  Issue : 2  |  Page : 381--385

Early recurrence of proliferative glomerulonephritis with monoclonal immunoglobulin deposits in a renal allograft


Rohit Tewari1, Kusum Joshi2, Ashwani Kumar2, CS Rayat2, Rajaram Iyer3, Vinay Sakhuja3, Mukut Minz4 
1 Department of Pathology, Armed Forces Medical College, Pune, Maharashtra, India
2 Department of Histopathology, Post Graduate Institute of Medical Education and Research, Chandigarh, India
3 Department of Nephrology, Post Graduate Institute of Medical Education and Research, Chandigarh, India
4 Department of Transplant Surgery, Post Graduate Institute of Medical Education and Research, Chandigarh, India

Correspondence Address:
Rohit Tewari
Department of Pathology, Armed Forces Medical College, Pune, Maharashtra
India

Proliferative glomerulonephritis with monoclonal immunoglobulin deposits (PGNMIDs) is a clinico-pathologic entity, the recurrence of which in the renal allograft has only recently been described. A 55-year-old male presented with rapid deterioration of renal function. Light microscopy showed membranoproliferative glomerulonephritis with kappa light chain restriction and only one sub-class of IgG. He subsequently underwent renal transplant. Two months later, he developed acute graft dysfunction. Renal biopsy showed a recurrence of the disease. Work up for multiple myeloma was positive. Membranoproliferative pattern of injury in the posttransplant setting has a wide range of differential diagnosis, PGNMID being one of them.


How to cite this article:
Tewari R, Joshi K, Kumar A, Rayat C S, Iyer R, Sakhuja V, Minz M. Early recurrence of proliferative glomerulonephritis with monoclonal immunoglobulin deposits in a renal allograft.Saudi J Kidney Dis Transpl 2016;27:381-385


How to cite this URL:
Tewari R, Joshi K, Kumar A, Rayat C S, Iyer R, Sakhuja V, Minz M. Early recurrence of proliferative glomerulonephritis with monoclonal immunoglobulin deposits in a renal allograft. Saudi J Kidney Dis Transpl [serial online] 2016 [cited 2019 Dec 6 ];27:381-385
Available from: http://www.sjkdt.org/article.asp?issn=1319-2442;year=2016;volume=27;issue=2;spage=381;epage=385;aulast=Tewari;type=0