Saudi Journal of Kidney Diseases and Transplantation

ORIGINAL ARTICLE
Year
: 2019  |  Volume : 30  |  Issue : 4  |  Page : 819--824

Calcification of abdominal aorta in patients recently starting hemodialysis: A single-center experience from Egypt


Ahmed Fayed, Mahmoud M Elnokeety, Khaled Attia, Usama A Sharaf El Din 
 Department of Internal Medicine, Nephrology Unit, School of Medicine, Cairo University, Cairo, Egypt

Correspondence Address:
Ahmed Fayed
Dr. Ahmed Fayed, Department of Internal Medicine, Nephrology Unit, School of Medicine, Cairo University, Cairo
Egypt

Vascular calcification (VC) is a well-known complication in patients with chronic kidney disease (CKD). Keeping in mind, the end goal to assess the genuine effect of mineral bone disease in the pathogenesis of blood vessel calcification during the pre-dialysis course of CKD, we assessed the prevalence and extent of abdominal aortic calcification (AAC) in nondiabetic CKD patients recently starting hemodialysis (HD). Eighty-one patients with end-stage renal disease beginning HD over a one-month period were selected. They underwent a detailed clinical examination and laboratory evaluation, including serum calcium, phosphorus, parathyroid hormone, fibroblast growth factor (FGF-23), and alkaline phosphatase were measured, and spiral computed tomography was performed to evaluate AAC score. AAC was present in 64 patients (79%). There was a significant correlation between the AAC score and age (r = 0.609, P <0.001) and FGF-23 (r = 0.800, P <0.001). This study suggests that the prevalence and extent of AAC are critical in incident HD patients. Serum FGF-23 level is the sole statistically significant correlate of AAC in these patients.


How to cite this article:
Fayed A, Elnokeety MM, Attia K, Sharaf El Din UA. Calcification of abdominal aorta in patients recently starting hemodialysis: A single-center experience from Egypt.Saudi J Kidney Dis Transpl 2019;30:819-824


How to cite this URL:
Fayed A, Elnokeety MM, Attia K, Sharaf El Din UA. Calcification of abdominal aorta in patients recently starting hemodialysis: A single-center experience from Egypt. Saudi J Kidney Dis Transpl [serial online] 2019 [cited 2019 Oct 19 ];30:819-824
Available from: http://www.sjkdt.org/article.asp?issn=1319-2442;year=2019;volume=30;issue=4;spage=819;epage=824;aulast=Fayed;type=0