Saudi Journal of Kidney Diseases and Transplantation

RENAL DATA FROM ASIA–AFRICA
Year
: 2019  |  Volume : 30  |  Issue : 5  |  Page : 1131--1136

Associated factors of dialysis-dependence among acute kidney injury patients in intensive care unit


Mardhiah Kamaruddin1, Siti-Azrin Ab Hamid2, Azreen Syazril Adnan3, Nyi Nyi Naing4, Wan-Nor-Asyikeen Wan Adnan2 
1 Unit of Biostatistics and Research Methodology; Faculty of Entrepreneurship and Business, Universiti Malaysia Kelantan, Kelantan, Malaysia
2 Unit of Biostatistics and Research Methodology, Universiti Sains Malaysia, Kelantan, Malaysia
3 Chronic Kidney Disease Resources Center, Universiti Sains Malaysia, Kelantan; Management and Science University, MSU Medical Centre, Selangor, Malaysia
4 Faculty of Medicine, Universiti Sultan Zainal Abidin, Medical Campus, Terengganu, Malaysia

Correspondence Address:
Siti-Azrin Ab Hamid
Unit of Biostatistics and Research Methodology, School of Medical Sciences, Universiti Sains Malaysia, 16150, Kubang Kerian, Kelantan
Malaysia

Acute kidney injury (AKI) is a common problem in hospitals and many end up requiring dialysis. The aim was to identify the associated factors of dialysis-dependent of AKI patients admitted to the intensive care units (ICUs). A retrospective cohort study was conducted where a list of 121 AKI patients admitted to ICU in Hospital Universiti Sains Malaysia was retrospectively reviewed. AKI patients aged below 18 years old, had kidney transplantation or chronic dialysis before ICU admission and had incomplete medical record were excluded from the study. Simple and multiple logistic regression analysis were used. The mean [standard deviation (SD)] age of patients was 56 (17.15) years. Majority of patients were males (63.2%) and Malay ethnic (54.1%). 49.3% of patients were in stage I, 48.3% in stage II and 76.2% in stage III. The mean (SD) duration of patients stayed in ICU was 7 days (6.92) for non-dialysis dependent and 12 days (8.37) for dialysis-dependent. The associated factors were male gender [adjusted odds ratio (OR): 3.68; 95% confidence interval [CI]: 1.53, 8.86; P = 0.004], AKI Stage III (adjusted OR: 4.51; 95% CI: 1.28, 15.91; P = 0.019), admitted in ICU (adjusted OR: 3.05; 95% CI: 1.28, 7.29; P = 0.012), and longer length of stay (adjusted OR: 1.10; 95% CI: 1.03, 1.18; P = 0.003). The factors influence of dialysis-requiring AKI were observed to be dependent on the male male gender, suffer from the advanced stage (Stage III), admitted to the ICU and had a longer length of stay in ICU. Therefore, it is important for physicians to identify patients who are at high risk of developing AKI and implement preventive strategies.


How to cite this article:
Kamaruddin M, Hamid SAA, Adnan AS, Naing NN, Wan Adnan WN. Associated factors of dialysis-dependence among acute kidney injury patients in intensive care unit.Saudi J Kidney Dis Transpl 2019;30:1131-1136


How to cite this URL:
Kamaruddin M, Hamid SAA, Adnan AS, Naing NN, Wan Adnan WN. Associated factors of dialysis-dependence among acute kidney injury patients in intensive care unit. Saudi J Kidney Dis Transpl [serial online] 2019 [cited 2020 Sep 24 ];30:1131-1136
Available from: http://www.sjkdt.org/article.asp?issn=1319-2442;year=2019;volume=30;issue=5;spage=1131;epage=1136;aulast=Kamaruddin;type=0