Figure 3: Serum creatinine concentrations. LPS injection increased serum creatinine concentration, while the medium and the highest doses of captopril decreased it. The data are shown as mean ± SEM. *P <0.05 compared to the control, +P <0.05 and +++P <0.001 compared to LPS, $$$P <0.001 compared to 10 mg/kg captopril, &&P <0.01 compared to 50 mg/kg captopril. LPS: Lipopolysaccharide, SEM: Standard error of the mean.