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Saudi Journal of Kidney Diseases and Transplantation
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ORIGINAL ARTICLE Table of Contents   
Year : 1995  |  Volume : 6  |  Issue : 3  |  Page : 294-297
Rhabdomyolysis and Acute Renal Failure in Head Injury Patients

1 Department of ICU, King Fahd Hospital, Madina Al-Munawarah, Saudi Arabia
2 Department of Nephrology, King Fahd Hospital, Madina Al-Munawarah, Saudi Arabia
3 Department of Laboratories, King Fahd Hospital, Madina Al-Munawarah, Saudi Arabia

Correspondence Address:
Bassam Bernieh
Department of Nephrology, King Fahd Hospital, Madina Al-Munawarah
Saudi Arabia
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PMID: 18583738

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Rhabdomyolysis is a known complication of crush injuries, but is not known to complicate the course of the patients with head injuries without other apparent skeletal muscle injuries. The frequency of renal failure may be high in such group of patients. We conducted a prospective study to evaluate such incidence on twenty patients with head injuries. Ten patients (50%) had other injuries in addition, but none of the patients had crush injury. All the patients were investigated daily for serum electrolytes, urea, creatinine, creatinine phosphokinase (CPK) and myoglobulinuria. All these patients were on a dehydrating protocol to prevent brain edema, including administration of dopamine infusion (1-3 g/kg/min), intravenous bolus doses of mannitol, and sodium bicarbonate. Nine patients (45%) developed renal impairment, three of them had no other apparent skeletal muscle injuries, but none of them required dialysis. Rhabdomyolysis is not uncommon in head injury patients in the absence of apparent skeletal muscle injuries, and may precipitate renal failure. This may have therapeutic implications to prevent the incidence of acute renal failure in such group of patients.

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