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Saudi Journal of Kidney Diseases and Transplantation
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CASE REPORT Table of Contents   
Year : 2000  |  Volume : 11  |  Issue : 1  |  Page : 53-58
Wolfram's (DIDMOAD) Syndrome and Chronic Renal Failure

Pediatric Unit, King Hussein Medical Center, Amman, Jordan

Correspondence Address:
Mojaly Ahmed Hasan
Pediatric Consultant, King Hussein Medical Center, P.O. Box 6080, El-Zarqa
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PMID: 18209300

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Wolfram's syndrome is usually considered as an autosomal recessive condition, with wide phenotypic variation. The syndrome is commonly called DIDMOAD (diabetes insipidus, diabetes mellitus, optic atrophy and deafness), although some patients have additional clinical findings including ataxia, hypogonadism, hydronephrosis and psychiatric illnesses. We report a patient with DIDMOAD syndrome with emphasis on the urological tract and its progressive complications. Unfortunately, he developed end-stage renal failure and needed hemodialysis at the age of 14 years. The presentation, investigations and management are discussed.

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