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Saudi Journal of Kidney Diseases and Transplantation
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Year : 2000  |  Volume : 11  |  Issue : 3  |  Page : 381-395
Management of Lupus Nephritis

Medical Clinic I, Cologne City Hospital, Cologne-Merheim, Germany

Correspondence Address:
M Weber
Medical Clinic I, Cologne City Hospital, Teaching Hospital University of Cologne, Ostmerheimerstr. 200, D-51109 Cologne
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PMID: 18209330

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Summary : Renal disease is common in systemic lupus erythematosus (SLE) and significantly influences patient prognosis. Immunosuppressive therapy has markedly improved outcome, however, it increases the risk of infection and cancer induction. Although several therapeutic regimens have proved to be effective in controlling lupus nephritis (LN), optimal therapy is still a matter of discussion. The following review summarizes our current knowledge in treating LN and discusses new aspects in pathogenesis. Hopefully, continuing progress in uncovering details about the pathogenesis of SLE might lead to more disease­specific approaches to treat the underlying immunological disorder.

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