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Saudi Journal of Kidney Diseases and Transplantation
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LETTER TO EDITOR Table of Contents   
Year : 2006  |  Volume : 17  |  Issue : 4  |  Page : 576-577
Renal Angiomyxoma

Department of Urology and Pathology, Shiraz University of Medical Sciences Shiraz, Iran

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How to cite this article:
Salehipour M, Geramizadeh B, Azizi V, Rajabi MJ, Boub R. Renal Angiomyxoma. Saudi J Kidney Dis Transpl 2006;17:576-7

How to cite this URL:
Salehipour M, Geramizadeh B, Azizi V, Rajabi MJ, Boub R. Renal Angiomyxoma. Saudi J Kidney Dis Transpl [serial online] 2006 [cited 2021 Jul 25];17:576-7. Available from: https://www.sjkdt.org/text.asp?2006/17/4/576/32499
Dear editor,

Angiomyxoma is a rare soft tissue tumor of the female pelvis and perineum involving the vulvar and perineal region with frequent local recurrence. Histologically, this tumor is rich in vascular structures and in collagen fibers and differentiation from myxoid lipo­sarcomas or fibrosarcomas may be difficult. Despite its benign histological appearance, the tumor exhibits a tendency for local, often multiple recurrences. [1] A 32-year-old female presented with a large mass in left flank. The patient had no history of fever, gross hematuria, trauma, lower urinary tract symptoms or pain. Physical examination revealed a large palpable slightly tender, smooth mass in the left flank. Urinalysis showed microhematuria. Urine culture, renal and liver function tests and blood chemistries were normal. Abdominal compu­terized tomography (CT) showed a huge solid heterogeneous mass in the left kidney [Figure - 1]. The pathological evaluation of the radically nephrectomized left kidney revealed a myxoid hypocellular tumor with numerous small sized vessels with compressed lumen and also large dilated vessels [Figure - 2]. Some isolated stellate - like cells were also noted.

Angiomyxoma usually locally infiltrates the surrounding tissues with less tendency to metastasis. Although the vast majority of angiomyxoma occurs in females, Iezzoni et al. reported four cases of angiomyxoma in the scrotum of adult males. [2] Gondo et al reported a case of angiomyxoma of renal peripelvic soft tissue. [3] Since renal angiomyxoma presents usually as a mass, it should be considered in the differential diagnosis of all renal neo­plasms. Complete resection of tumor is the treatment of choice. In pelvic angiomyxoma with a positive estrogen and progesterone receptors, treatment with gonadotropin-releasing hormone agonists may prevent recurrence. [4]

   References Top

1.Steeper TA, Rosai J. Aggressive angiomyxoma of the female pelvis and perineum: Report of nine cases of a distinctive type of gynecologic soft tissue neoplasm. Am J Surg Pathol 1983;7:463-75.  Back to cited text no. 1  [PUBMED]  
2.Iezzoni JC, Fechner RE, Wong LS, Rosai J.: Aggressive angiomyxoma in males: A report of four cases. Am J Clin Pathol 1995;104:391-6.  Back to cited text no. 2  [PUBMED]  
3.Gondo T, Takahashi M, Hoshii Y, Iwata T, Kashiwagi T, Ishihara T. Angiomyoxoid tumour in the renal peripelvic tissues with features of aggressive angio-myxoma. J Clin Pathol 1995;48:82-3.  Back to cited text no. 3  [PUBMED]  [FULLTEXT]
4.Fine BA, Munoz AK, Litz CE, Gershenson DM. Primary medical management of recurrent aggressive angiomyxoma of the vulva with a gonadotropin-releasing hormone agonist. Gynecol Oncol 2001;81:120-2.  Back to cited text no. 4  [PUBMED]  [FULLTEXT]

Correspondence Address:
Mehdi Salehipour
Department of Urology and Pathology, Shiraz University of Medical Sciences Shiraz
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PMID: 17186696

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