Home About us Current issue Back issues Submission Instructions Advertise Contact Login   

Search Article 
Advanced search 
Saudi Journal of Kidney Diseases and Transplantation
Users online: 1459 Home Bookmark this page Print this page Email this page Small font sizeDefault font size Increase font size 

Year : 2008  |  Volume : 19  |  Issue : 3  |  Page : 461-465
Hepatitis C virus Genotypes in Patients with End-Stage Renal Disease in East Azerbaijan, Iran

1 Liver and Gastrointestinal Diseases Research Center, Tabriz University of Medical Sciences, Tabriz, Iran
2 Department of Virology, Iran University of Medical Sciences, Tehran, Iran

Correspondence Address:
Sara Farhang
Liver and Gastrointestinal Diseases Research Center, Imam Hospital, Tabriz, East Azerbaijan
Login to access the Email id

PMID: 18445914

Rights and Permissions

Information about the genotypes and associated risk factors in hepatitis C virus (HCV) infected patients in Iran is limited. The aim of this study was to identify the HCV genotypes and associated risk factors in a group of HCV infected patients on dialysis therapy in Iran. The sera of 753 patients with chronic renal failure from fifteen dialysis units in East Azerbaijan Province were screened for anti-HCV antibodies as well as HCV RNA; viral RNA was extracted for the genotype specific primer approach. Patients were questioned concerning documented risk factors. Genotyping analysis was performed in 55 patients with positive anti-HCV and HCV-RNA. Genotypes 1 and 3 were found in 46 (83.7%) and three (5.5%) patients, respectively. The most frequent HCV subtype was 1a (76.4%), followed by 3a and 1b and 1b (5.5% each) while one patient was infected with both 1a and 1b. There was no statistically significant difference between the risk factors analyzed and the acqui­sition of HCV infection. This study gives added evidence of the predominant HCV genotypes in Iran, which is different than reports from other Arab countries and similar with the pattern of genotype in both Europe and United States.

Print this article  Email this article

  Similar in PUBMED
    Search Pubmed for
    Search in Google Scholar for
  Related articles
   Citation Manager
  Access Statistics
   Reader Comments
   Email Alert *
   Add to My List *
 * Requires registration (Free)

 Article Access Statistics
    PDF Downloaded519    
    Comments [Add]    
    Cited by others 8    

Recommend this journal