Home About us Current issue Back issues Submission Instructions Advertise Contact Login   

Search Article 
Advanced search 
Saudi Journal of Kidney Diseases and Transplantation
Users online: 1546 Home Bookmark this page Print this page Email this page Small font sizeDefault font size Increase font size 

CASE REPORT Table of Contents   
Year : 2009  |  Volume : 20  |  Issue : 4  |  Page : 652-654
Tri-filial presentation of familial tuberous sclerosis with renal tumors

1 Department of General Surgery, Midnapore Medical College and Hospital, Midnapore, West Bengal, India
2 Department of Dermatology, Midnapore Medical College and Hospital, Midnapore, West Bengal, India
3 Department of Pathology, Midnapore Medical College and Hospital, Midnapore, West Bengal, India

Correspondence Address:
Swarup Chakraborty
Department of General Surgery, Midnapore Medical College & Hospital, Midnapore 721001, West Bengal
Login to access the Email id

PMID: 19587510

Rights and Permissions

Tuberous sclerosis is a rare neuro-cutaneous syndrome with autosomal dominant penetrance. Only some organs are involved, e.g., skin (earthy skin thickenings, ash leaf patches), cerebral cortex (hamartomatous nodules) and kidneys, (angiolipoma, adenocarcinoma). These hamar­tomatous swellings resemble potatoes and hence, referred to as tubers. We herein report on three patients (all familial), father, son and granddaughter, with this rare involvement, from the eastern part of India. The father and son had involvement of only the skin (i.e. nose) and kidneys while the disease penetrated further in the subsequent filial generations with son and granddaughter having skin, brain and bilateral kidney involvement. This kind of tri-filial progression has not till date, been reported from this region, making it an interesting case presentation.

Print this article  Email this article

  Similar in PUBMED
    Search Pubmed for
    Search in Google Scholar for
  Related articles
   Citation Manager
  Access Statistics
   Reader Comments
   Email Alert *
   Add to My List *
 * Requires registration (Free)

 Article Access Statistics
    PDF Downloaded377    
    Comments [Add]    

Recommend this journal