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Saudi Journal of Kidney Diseases and Transplantation
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CASE REPORT Table of Contents   
Year : 2009  |  Volume : 20  |  Issue : 5  |  Page : 842-845
Granulomatous interstitial nephritis due to tuberculosis-a rare presentation


1 Department of Nephrology, Meenakshi Mission Hospital and Research Centre, Lake Area, Melur Road, Madurai, Tamil Nadu, India
2 Department of Pathology, Amrita Institute of Medical Sciences, Amrita Lane, Elamakkara Post, Kochi, Kerala, India
3 Department of Molecular Biology, Amrita Institute of Medical Sciences, Amrita Lane, Elamakkara Post, Kochi, Kerala, India

Correspondence Address:
Krishnaswamy Sampathkumar
Department of Nephrology, Meenakshi Mission Hospital and Research Centre, Lake Area, Melur Road, Madurai, TamilNadu - 625 107
India
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PMID: 19736486

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Granulomatous interstitial nephritis (GIN) is an uncommon form of acute interstitial nephritis. We report a young male who presented to us with a rapidly progressing renal failure and massive proteinuria. A renal biopsy revealed GIN, and we were able to demonstrate the presence of tuberculous DNA in the biopsy specimen. The patient was started on anti-tuberculous therapy and steroids besides 11 sessions of hemodialysis. He recovered and is currently doing well. This case highlights an uncommon manifestation of renal tuberculosis, namely massive proteinuria, acute renal failure, and granulomatous interstitial lesions.


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