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Saudi Journal of Kidney Diseases and Transplantation
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Year : 2010  |  Volume : 21  |  Issue : 2  |  Page : 363-367
Survey the seroprevalence of CMV among hemodialysis patients in Urmia, Iran

1 Student's Research Committee, Urmia University of Medical Sciences, Urmia, Iran
2 Department of Microbiology, School of Paramedicine, Urmia University of Medical Sciences, Urmia, Iran
3 Department of Public Health, Urmia University of Medical Sciences, Urmia, Iran

Correspondence Address:
Zakieh Rostamzadeh Khameneh
Department of Microbiology, School of Paramedicine, Urmia University of Medical Sciences, Urmia, West-Azerbaijan
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Source of Support: None, Conflict of Interest: None

PMID: 20228534

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Cytomegalovirus (CMV) causes infection in immunocompromised, transplant reci­pients and those who received blood transfusion frequently. Risk factors for primary CMV infec­tion are blood transfusion (including clotting factors, etc), recipients of infected transplants, hemo­dialysis and the frequency of dialysis in a week. This study aimed at determining the prevalence of cytomegalovirus (CMV) antibodies in end-stage renal disease (ESRD) patients who undergo hemodialysis. A cross-sectional study of hemodialysis patients in Urmia, Iran was undertaken in 2007. Sera of 84 Hemodialysis patients were investigated for CMV-specific immunoglobulin G (IgG). Forty-four (52%) patients were males. 65 patients (77.4%) were anti-CMV IgG positive and 6 (7.1%) were anti-CMV IgM positive. There was no relationship between the antibody titer and dialysis duration, or frequency of HD in a week. In conclusion, we recommend that every patient who has undergone hemodialysis receive blood products free of CMV if CMV negative to reduce the incidence and prevalence of CMV among HD patients.

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