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Saudi Journal of Kidney Diseases and Transplantation
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BRIEF COMMUNICATION Table of Contents   
Year : 2010  |  Volume : 21  |  Issue : 4  |  Page : 707-711
Relation of serum albumin and C-reactive protein to hypotensive episodes during hemodialysis sessions


1 Department of Internal Medicine, Shiraz Nephro-Urology Research Center, Shiraz University of Medical Sciences, Shiraz, Iran
2 Interventional Electrophysiology, Fars Heart Foundation, Shiraz, Iran
3 Department of Biostatistics, Shiraz Nephro-Urology Research Center, Shiraz University of Medical Sciences, Shiraz, Iran
4 Kousar Hospital, Shiraz, Iran

Correspondence Address:
Leila Malekmakan
Nephro-Urology Research Center, Shiraz University of Medical Sciences, P.O. Box 71348-14336, Shiraz
Iran
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PMID: 20587876

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To evaluate the effect of albumin serum levels and C-reactive protein (CRP) on the course of dialysis induced hypotension (DIH) in chronic hemodialysis (HD) patients, we studied 58 chronic hemodialysis patients in our center during 2007. We investigated the correlation bet­ween serum albumin, highly sensitive CRP (hs-CRP) and DIH. The mean of the serum albumin levels was 4.2 ± 0.5 g/dL, and 32.8% of the patients revealed hypoalbuminemia. Occurrence of DIH among HD patients was 27.6%. The mean of serum albumin levels in the DIH group was significantly lower compared with the normotensive group (3.9 ± 0.4 vs 4.3 ± 0.5g/dL, respec­tively, P= 0.008). The mean of the hs-CRP levels was significantly higher in the DIH group compared with the normotensive group (12.9 ± 12 vs. 7.2 ± 5.2 mg/dL, respectively, P= 0.01). We conclude that high level of CRP and hypoalbuminemia may be predictors of DIH.


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