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Saudi Journal of Kidney Diseases and Transplantation
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CASE REPORT Table of Contents   
Year : 2011  |  Volume : 22  |  Issue : 1  |  Page : 123-125
Nephritic-nephrotic syndrome as a presentation of BK virus infection

Shiraz Nephro-Urology Research Center, Shiraz University of Medical Sciences, Shiraz, Iran

Correspondence Address:
Nima Derakhshan
71937-Pediatric Section, Nemazi Hospital, Shiraz
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PMID: 21196627

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BK virus (BKV) is increasingly found as an important cause of allograft nephro­pathy. Nephrotic syndrome is not a usual manifestation of BKV nephropathy. Here, we report a 12­year-old boy, a case of end-stage renal disease due to nephronophthisis, who got the kidney trans­planted from a 16-year-old cadaver, and after 18 months of uneventful transplantation on triple immunosuppressive therapy (Mycophenolate mofetil (MMF), cyclosporin and prednisolone), pre­sented with nephrotic feature (edema, heavy proteinuria, hypoalbuminemia and hyperlipidema). Kidney biopsy was in favor of BKV infection and eventually ended in graft failure.

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