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| Year : 2011 | Volume
: 22
| Issue : 2 | Page : 345-346 |
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| Renal biopsies in glomerular diseases |
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Abdul Hakeem Attar, MN Jadhav, B Zeenath, RM Madraki, BR Yelikar
Department of Pathology, Shri B. M. Patil Medical College, Bijapur and KBNIMS, Gulbarga, India
Click here for correspondence address and email
| Date of Web Publication | 18-Mar-2011 |
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How to cite this article:
Attar AH, Jadhav M N, Zeenath B, Madraki R M, Yelikar B R. Renal biopsies in glomerular diseases. Saudi J Kidney Dis Transpl 2011;22:345-6 |
How to cite this URL:
Attar AH, Jadhav M N, Zeenath B, Madraki R M, Yelikar B R. Renal biopsies in glomerular diseases. Saudi J Kidney Dis Transpl [serial online] 2011 [cited 2021 Jan 17];22:345-6. Available from: https://www.sjkdt.org/text.asp?2011/22/2/345/77629 |
To the Editor,
Renal biopsy is the corner stone for diagnosis of glomerular diseases, which not only provides precise diagnosis, but also helps in the treatment and the assessment of the prognosis. Percutaneous gun biopsies have a higher diagnostic yield with fewer complications. We studied the spectrum of glomerular diseases in our hospital from August 2005 to August 2007. We studied 40 renal biopsies using 18-Gauge "Bard's bioptic gun", and adequate tissue was obtained in 97.5% patients. The sections of the specimens were stained with hematoxylin and eosin; special stains and immunofluorescence were used whenever necessary. Focal segmental glomerulosclerosis (FSGS) was most common accounting for 25% of cases, followed by mesangioproliferative glomerulonephritis (GN) in 22.5% of cases. Among the secondary glomerular diseases, amyloidosis accounted for 10% of cases. [Table 1] shows the distribution of the GN in our study patients. | Table 1: Incidence of primary and secondary glomerulonephritis (GN) in our study patients.
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It seems that the incidence of FSGS increased over the past two decades as reported elsewhere. [1],[2],[3],[4],[5],[6],[7],[8] Minimal change disease is common below the age of 10 years.
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| 1. | Braden GL, Mulhern JG, O'Shea MH, Nash SV, Ucci AA Jr, Germain MJ. Changing incidence of glomerular diseases in adults. Am J Kidney Dis 2000;35(5):878-83. 
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| 2. | Lynn K. Familial focal and segmental glomerulosclerosis. Indian J Nephrol 1999;4:130-4.
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| 3. | Abrantes MM, Cardoso LS, Lima EM, et al. Clinical course of 110 children and adolescents with primary focal segmental glomerulosclerosis. Pediatr Nephol 2006;21:482-9.
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| 4. | Rana K, Isbel N. Clinical, Histopathologic and Genetic studies in nine families with focal segmental glomerulosclerosis. Am J Kidney Dis 2003;4(6):1170-8.
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| 5. | Schwartz MM, Korbet MS. Current concepts in renal pathology. Am J Kidney Dis 1993;22(6):874-83.
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| 6. | Balakrishnan N, John GT, Korula A, et al. Spectrum of biopsy proven renal diseases and changing trends at a tropical tertiary care centre. Indian J Nephrol 2003;13:29-35.
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| 7. | Burstein MD, Korbet MS, Schwartz MM. The use of automatic core biopsy system in percutaneous renal biopsies: A comparative study. Am J Kidney Dis 1993;22:545-52.
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| 8. | Daskalakis N, Winn PM. Focal and segmental glomerulosclerosis: Varying biologic mechanisms underlie a final histopathologic end point. Semin Nephrol 2006;26:89-94.
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Correspondence Address:
B Zeenath
Department of Pathology, Shri B. M. Patil Medical College, Bijapur and KBNIMS, Gulbarga
India
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PMID: 21422641 
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