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Saudi Journal of Kidney Diseases and Transplantation
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Year : 2011  |  Volume : 22  |  Issue : 6  |  Page : 1226-1228
Acute urine retention induced by ceftriaxone

Department of Pediatrics Nephrology, Jordan University Hospital, Faculty of Medicine, University of Jordan, Amman, Jordan

Correspondence Address:
Kamal F Akl
Associate Professor of Pediatric Nephrology, Jordan University Hospital, Faculty of Medicine, University of Jordan, P.O. Box 831373 Amman 11183
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PMID: 22089789

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Ceftriaxone is known to cause biliary pseudolithiasis and, rarely, nephrolithiasis. When used in neonates receiving intravenous calcium, fatal lung and kidney calcifications occur. There is no satisfactory explanation for the pseudolithiasis, and the mechanism of stone formation remains unknown. Herein, we report a child with acute urinary retention (AUR) secondary to ceftriaxone therapy. The AUR developed on the second hospital day. The urinary excretion of uric acid was elevated. In retrospect, there was a positive paternal family history of gout and stones. A positive family history of gout or stones is a pointer to the possibility of AUR or urolithiasis in patients on treatment with ceftriaxone. If urinary symptoms develop, it is worth checking for crystalluria. This will avoid many unnecessary investigations and procedures.

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