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| Year : 2012 | Volume
: 23
| Issue : 1 | Page : 151 |
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| Author's Reply |
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Dipankar M Bhowmik1, Sheelbhadra Jain1, Amik K Dinda2, Alok Sharma2, Sandeep Mahajan1, Sanjay K Agarwal1
1 Department of Nephrology, All India Institute of Medical Sciences, New Delhi, India
2 Department of Pathology, All India Institute of Medical Sciences, New Delhi, India
Click here for correspondence address and email
| Date of Web Publication | 3-Jan-2012 |
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How to cite this article:
Bhowmik DM, Jain S, Dinda AK, Sharma A, Mahajan S, Agarwal SK. Author's Reply. Saudi J Kidney Dis Transpl 2012;23:151 |
To the Editor ,
We thank Dr. Muhammed Mubarak [1] for his keen interest in our article, [2] and his very illuminating comments. Our responses to his specific queries are as follows:
- We agree that it was a mistake to call C1q an immunoglobulin. C1q is a component of the complement system.
- The intensity of staining of C1q was 3+, while there was minimal focal staining of IgG and IgM.
- The mesangial proliferation was 4-6 cells/mesangial area.
- EM was not done in this case, as we felt that EM would not be confirmatory in this case.
- Subsequent to publication, we have information that there have been no further episodes of hematuria, and the nephrotic syndrome continues to remain in remission. There are no features of lupus as yet. Prednisolone has been tapered and stopped.
- We agree that a firm diagnosis of C1q nephropathy requires a correlation of clinical and pathological data.
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| 1. | Mubarak M. C1q Nephropathy presenting as Nephritic-Nephrotic syndrome. Saudi J Kidney Dis Transpl 2012;23(1):150-1. 
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| 2. | Bhowmik DM, Jain S, Dinda AK, Sharma A, Mahajan S, Agarwal SK. C1q nephropathy presenting as nephritic-nephrotic syndrome. Saudi J Kidney Dis Transpl 2011;22(3):561-3.
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Correspondence Address:
Dipankar M Bhowmik
Department of Nephrology, All India Institute of Medical Sciences, New Delhi
India
 Source of Support: None, Conflict of Interest: None  | Check |
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