Home About us Current issue Ahead of Print Back issues Submission Instructions Advertise Contact Login   

Search Article 
Advanced search 
Saudi Journal of Kidney Diseases and Transplantation
Users online: 3634 Home Bookmark this page Print this page Email this page Small font sizeDefault font size Increase font size 

CASE REPORT Table of Contents   
Year : 2013  |  Volume : 24  |  Issue : 4  |  Page : 764-767
Esophageal histoplasmosis in a renal allograft recipient

1 Department of Nephrology, SMS Hospital and Medical College, Jaipur, India
2 Department of Pathology, S. R. Kalla Memorial Gastro and General Hospital, Jaipur, India
3 Department of Gastroenterology, S. R. Kalla Memorial Gastro and General Hospital, Jaipur, India
4 Department of Nephrology, S. R. Kalla Memorial Gastro and General Hospital, Jaipur, India

Correspondence Address:
S S Gupta
Department of Nephrology, SMS Medical College and Hospital, Jaipur - 302 004
Login to access the Email id

Source of Support: None, Conflict of Interest: None

DOI: 10.4103/1319-2442.113874

Rights and Permissions

Histoplasmosis is a progressive granulomatous disease caused by the intracellular dimorphic fungus Histoplasma capsulatum. We report a rare case of esophageal histoplasmosis in a renal allograft recipient. A 55-year-old male who received a live, unrelated renal allograft 20 years ago presented with complaints of recurrent fever for ten to 12 months, weight loss over six months, progressive dysphagia more for solids for five to six months and joint pain and swelling involving the bilateral metacarpo-phalangeal and proximal interphalangeal joints. Biopsy from the esophageal ulcers revealed dense inflammation infiltrated with lymphocytes and macrophages with clusters of strongly positive intracellular fungal spores with a clear area or "halo-like" zone suggestive of Histoplasma capsulatum invasion. The patient was treated with intravenous liposomal amphotericin B for ten days and later switched over to oral itraconazole. Repeated endoscopy revealed significant improvement of the lesions.

Print this article  Email this article

  Similar in PUBMED
    Search Pubmed for
    Search in Google Scholar for
   Citation Manager
  Access Statistics
   Reader Comments
   Email Alert *
   Add to My List *
 * Requires registration (Free)

 Article Access Statistics
    PDF Downloaded335    
    Comments [Add]    
    Cited by others 2    

Recommend this journal