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Saudi Journal of Kidney Diseases and Transplantation
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CASE REPORT Table of Contents   
Year : 2014  |  Volume : 25  |  Issue : 2  |  Page : 381-384
Sodium hypochlorite-induced acute kidney injury

1 Department of Medicine, Baylor College of Medicine, Houston, TX, USA
2 Department of Medicine; Division of Nephrology, Baylor College of Medicine, Houston, TX, USA

Correspondence Address:
Abdul Abdellatif
Division of Nephrology, Department of Medicine, Baylor College of Medicine, Houston, TX, 77030
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DOI: 10.4103/1319-2442.128553

PMID: 24626008

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Sodium hypochlorite (bleach) is commonly used as an irrigant during dental proce­dures as well as a topical antiseptic agent. Although it is generally safe when applied topically, reports of accidental injection of sodium hypochlorite into tissue have been reported. Local necrosis, pain and nerve damage have been described as a result of exposure, but sodium hypo­chlorite has never been implicated as a cause of an acute kidney injury (AKI). In this report, we describe the first case of accidental sodium hypochlorite injection into the infraorbital tissue during a dental procedure that precipitated the AKI. We speculate that oxidative species induced by sodium hypochlorite caused AKI secondary to the renal tubular injury, causing mild acute tubular necrosis.

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