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Saudi Journal of Kidney Diseases and Transplantation
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Year : 2015  |  Volume : 26  |  Issue : 1  |  Page : 152
Chinese H7N9 bird flu: A concern on kidney involvement

1 Wiwanitkit House, Bangkhae, Bangkok, Thailand
2 Hainan Medical University, China

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Date of Web Publication8-Jan-2015

How to cite this article:
Wiwanitkit S, Wiwanitkit V. Chinese H7N9 bird flu: A concern on kidney involvement. Saudi J Kidney Dis Transpl 2015;26:152

How to cite this URL:
Wiwanitkit S, Wiwanitkit V. Chinese H7N9 bird flu: A concern on kidney involvement. Saudi J Kidney Dis Transpl [serial online] 2015 [cited 2021 Feb 28];26:152. Available from: https://www.sjkdt.org/text.asp?2015/26/1/152/148768
To the Editor,

In April 2013, the new emerging H7N9 flu in China became the hot topic in the medical society. [1] This new zoonosis is an atypical influenza infection. In addition to the classical symptoms of acute febrile illness with respiratory problems, there are also other atypical clinical presentations. [2],[3] Other organ involvements including renal involvement have been mentioned. [2],[3] A common cause of death in these patients is renal failure, although it is questionable whether this is a complication of the respiratory illness or a pathology due to direct viral invasion. [4] Indeed, the problem of renal involvement in bird flu has been described since the previous outbreak of H5N1 bird flu. [5] The interesting consideration is on the renal pathology. The common renal pathology encountered in H5N1 bird flu is acute renal tubular necrosis. [6] For the present situation, renal involvement and pathology in cases with H7N9 presenting with renal failure is an interesting topic for further study in nephrology. At present, there is only a data from an autopsy case that hypoxic change of kidney is the only observed renal pathology. [7]

Conflict of interest: None

   References Top

Eurosurveillance editorial team. Novel influenza A(H7N9) virus linked to human disease in China, April 2013. Euro Surveill 2013;18:14.  Back to cited text no. 1
Lu SH, Xi XH, Zheng YF, Cao Y, Liu XN, Lu HZ. Analysis of the clinical characteristics and treatment of two patients with avian influenza virus (H7N9). Biosci Trends 2013;7:109-12.  Back to cited text no. 2
Gao R, Cao B, Hu Y, et al. Human Infection with a Novel Avian-Origin Influenza A (H7N9) Virus. N Engl J Med 2013;368:1888-97.  Back to cited text no. 3
Wiwanitkit V. Renal failure in the new H7N9 influenza: a topic for further study. Ren Fail 2013;35:1466.  Back to cited text no. 4
Wiwanitkit V. Level of blood creatinine in the recent reported cases of bird flu infection in Thailand and Vietnam. Nephrology (Carlton) 2005;10:425.  Back to cited text no. 5
To KF, Chan PK, Chan KF, et al. Pathology of fatal human infection associated with avian influenza A H5N1 virus. J Med Virol 2001;63:242-6.  Back to cited text no. 6
Yu L, Wang Z, Chen Y, et al. Clinical, virological, and histopathological manifestations of fatal human infections by avian influenza A (H7N9) virus. Clin Infect Dis 2013;57:1449-57.  Back to cited text no. 7

Correspondence Address:
Dr. Somsri Wiwanitkit
Wiwanitkit House, Bangkhae, Bangkok
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DOI: 10.4103/1319-2442.148768

PMID: 25579740

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