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Saudi Journal of Kidney Diseases and Transplantation
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Year : 2015  |  Volume : 26  |  Issue : 1  |  Page : 90-93
Evaluation of thyroid hormone levels in chronic kidney disease patients


1 Department of Biochemistry, Akash Institute of Medical Sciences and Research Centre, Bangalore, India
2 Department of Biochemistry, NRI Medical College and General Hospital, Guntur, India
3 Department of Biochemistry, Dhanalakshmi Srinivasan Medical College and Hospital, Perambalur, India
4 Department of Nephrology, NRI Medical College and General Hospital, Guntur, India

Correspondence Address:
Dr. Wilma Delphine Silvia Chickballapur Rayappa
Department of Biochemistry, Akash Institute of Medical Sciences and Research Centre, Devanahalli, Bangalore -562110, Karnataka
India
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DOI: 10.4103/1319-2442.148749

PMID: 25579722

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We attempted in this study to determine the thyroid hormone levels in 45 adult chronic kidney disease (CKD) patients and 45 ageand sex-matched healthy subjects as controls. The serum thyroid hormone levels were measured by a radioimmunoassay. Serum concentrations of creatinine, urea, electrolytes and total proteins and albumin were measured as well. There was a significant decrease in the levels of serum total T3, total T4 and total protein and albumin levels in CKD patients when compared with the controls. There was a significant increase in the level of thyroid stimulating hormone in the CKD patients compared with the controls. Our study suggests that CKD leads to significant changes in the thyroid hormone levels, which need to be interpreted carefully in these patients.


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